Synthesis and stability of vinyl ketones in the 2-position of benzofuran was written by Faure, Robert;Mattioda, Georges. And the article was included in Bulletin de la Societe Chimique de France in 1973.Product Details of 38220-75-6 This article mentions the following:
2-Benzofuryl vinyl ketones I (R = H, Me, Et; R1 = Me; R2 = H, OMe, Cl) were prepared by Mannich reaction of 2-acylbenzofurans and hydrolysis of the Mannich bases. I (R1 = H) were too unstable to be isolated before they polymerized In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Product Details of 38220-75-6).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. As benzofurans are prone to undergo ring opening of the heterocycle, examples of reduction of this type of aromatics by using dissolving metals are rather scarce.Product Details of 38220-75-6
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem