Synthetic Route of C19H19N2NaO2. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide, is researched, Molecular C19H19N2NaO2, CAS is 129-18-0, about Effect of meseclazone and other non-steroidal antiinflammatory drugs on isolated tracheal chain tone. Author is Diamantis, William; Melton, John L.; Sofia, R. Duane; Ciofalo, Vincent B..
Concentration-dependent relaxation of the isolated guinea pig tracheal chain was produced by the following nonsteroidal antiinflammatory drugs: naproxen [22204-53-1] > ibuprofen [15687-27-1] > diflunisal [22494-42-4] > tolmetin [26171-23-3] ≃ fenoprofen [29679-58-1] ≃ indomethacin [53-86-1] > phenylbutazone Na [129-18-0] > meseclazone (I) [29053-27-8] > 5-chlorosalicylic acid [321-14-2] > aspirin [50-78-2]. All these drugs were less potent than isoproterenol-HCl. This relaxation may be related to inhibition of prostaglandin synthesis, but since the relative potencies of the drugs in the tracheal test did not necessarily correspond to those in inhibiting prostaglandin synthetase in other tissues, other factors may be involved.
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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem