Rapid and selective determination of multi-sulfonamides by high-performance thin layer chromatography coupled to fluorescent densitometry and electrospray ionization mass detection was written by Chen, Yisheng;Schwack, Wolfgang. And the article was included in Journal of Chromatography A in 2014.COA of Formula: C17H10O4 This article mentions the following:
Sulfonamides are widely used in animal husbandry and monitoring their residues in edible animal tissues is important for food safety and quality control. A simple and efficient high-performance thin-layer chromatog. (HPTLC) anal. method for rapid screening of 12 veterinary sulfonamide drugs was developed. Sample acetonitrile extracts were 10-fold concentrated and applied to HPTLC without any further cleanup. Following separation and fluram derivatization, sensitive and selective quantitation of the analytes was readily accomplished with fluorescence densitometry. Limits of detection and quantitation were 15-40 and 35-70 μg/kg, resp. Confirmative detection by HPTLC-electrospray ionization mass spectrometry (HPTLC-ESI/MS) was optimized for straightforward identification of target TLC zones to decrease the risk of potential false pos. findings. The method was validated for different matrix complexities (cow milk, pork liver and kidney). In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9COA of Formula: C17H10O4).
4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.COA of Formula: C17H10O4
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem