Category: benzofurans

Recommanded Product: 87-41-2. I found the field of Chemistry very interesting. Saw the article Thiyl radical promoted iron-catalyzed-selective oxidation of benzylic sp(3) C-H bonds with molecular oxygen published in 2019, Reprint Addresses He, Y; Feng, Z (corresponding author), Chongqing Univ, Chongqing Key Lab Nat Prod Synth & Drug Res, Sch Pharmaceut Sci, Chongqing 401331, Peoples R China.; Feng, Z (corresponding author), Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

A ligand-free iron-catalyzed method for the oxygenation of benzylic sp(3) C-H bonds by molecular oxygen (1 atm) using a thiyl radical as a cocatalyst has been developed. This transformation provides a facile access to amides, esters and ketones from readily accessible corresponding amines, ethers and alkanes. It features high regioselectivity, mild oxidative conditions and excellent functional group compatibility, providing good opportunities to the site-selective functionalization of complex molecules. Preliminary mechanistic studies suggest that this reaction may not undergo a benzylic cation intermediate pathway and the carbonyl oxygen atom in the products may be derived from molecular oxygen.

Welcome to talk about 87-41-2, If you have any questions, you can contact Geng, SS; Xiong, BJ; Zhang, Y; Zhang, J; He, Y; Feng, Z or send Email.. Recommanded Product: 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3 WOS:000565183600002 published article about ISCHEMIA/REPERFUSION INJURY; INFLAMMASOME ACTIVATION; LIGUSTILIDE; STROKE; NEUROTOXICITY; PATHWAY; RATS in [Li, Xin; Shi, Meng-Qi; Du, Jun-Rong] Sichuan Univ, Educ Minist, Sichuan Engn Lab Plant Sourced Drug, Dept Pharmacol,Key Lab Drug Targeting & Drug Deli, Chengdu 610041, Peoples R China; [Li, Xin; Shi, Meng-Qi; Du, Jun-Rong] Sichuan Univ, West China Sch Pharm, Sichuan Res Ctr Drug Precis Ind Technol, Chengdu 610041, Peoples R China; [Chen, Chu] Sichuan Acad Chinese Med Sci, Chengdu 610041, Peoples R China in 2020, Cited 43. Product Details of 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

The activation of NLRP3 inflammasome is closely related to ischemic brain injury and inhibition of NLRP3 inflammasome activation may be a new therapeutic strategy for ischemic stroke. Our previous studies showed that ligustilide (LIG) had a dose-dependent neuroprotective effect on various models of cerebral ischemia and dementia in vivo and in vitro. CD21, a kind of phthalide derivative, was modified from LIG. In this study, we established a global cerebral ischemia-reperfusion model in mice by bilateral common carotid artery ligation (2VO), and explored the neuroprotective effect of CD21 and its anti-inflammatory mechanism on cerebral ischemia mice. CD21 significantly improved weight loss, neurobehavioral deficits and neurons loss in hippocampal CA1 and caudate putamen (CPu) subregions, which were induced by 2VO in mice. CD21 significantly inhibited the overactivation of astrocyte and microglia, and decreased the mRNA level of IL-6, TNF-alpha and IL-1 beta. Moreover, CD21 significantly inhibited the activation of TLR4/NF-kappa B signaling pathway mediated by HMGB1 and NLRP3/ASC/Caspase-1 signaling pathway mediated by Cathepsin B, thus inhibiting the activation of NLRP3 inflammasome. Our results demonstrated that CD21 may exert a neuroprotection by inhibiting NLRP3 inflammasome activation after cerebral ischemia. These findings provide a new strategy for the treatment of ischemic stroke.

Welcome to talk about 87-41-2, If you have any questions, you can contact Li, X; Shi, MQ; Chen, C; Du, JR or send Email.. Product Details of 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

HPLC of Formula: C8H6O2. In 2020 ORG BIOMOL CHEM published article about AEROBIC OXIDATION; SELECTIVE OXIDATION; ETHERS; COPPER; ISOCOUMARINS; PHTHALIDES; ALKANES in [Thatikonda, Thanusha; Deepake, Siddharth K.; Kumar, Pawan; Das, Utpal] CSIR Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India; [Deepake, Siddharth K.; Kumar, Pawan; Das, Utpal] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India in 2020, Cited 38. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

A metal-free organocatalytic system has been developed for highly efficient benzylic C-H oxygenations of cyclic ethers using oxygen as an oxidant. This oxidation reaction utilizes alpha-angelica lactone as a low cost/low molecular weight catalyst. The optimized reaction conditions allow the synthesis of valued isocoumarins and phthalides from readily available precursors in good yields. Mechanistic studies indicate that the reaction pathway likely involves a radical process via a peroxide intermediate.

Welcome to talk about 87-41-2, If you have any questions, you can contact Thatikonda, T; Deepake, SK; Kumar, P; Das, U or send Email.. HPLC of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Synthesis of polyoxymethylene dimethyl ethers from dimethoxymethane and trioxymethylene over graphene oxide: Probing the active species and relating the catalyst structure to performance WOS:000457661500002 published article about ACID IONIC LIQUIDS; EFFICIENT SYNTHESIS; CHEMICAL-EQUILIBRIUM; METHANOL; REDUCTION; SITES; OME; PARAFORMALDEHYDE; IMPROVEMENT; TRIOXANE in [Wang, Ruiyi; Wu, Zhiwei; Li, Zhikai; Qin, Zhangfeng; Chen, Chengmeng; Zheng, Zhanfeng; Wang, Guofu; Fan, Weibin; Wang, Jianguo] Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, POB 165, Taiyuan 030001, Shanxi, Peoples R China; [Chen, Chengmeng] Chinese Acad Sci, Inst Coal Chem, Key Lab Carbon Mat, Taiyuan 030001, Shanxi, Peoples R China in 2019, Cited 48. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. HPLC of Formula: C8H6O2

Polyoxymethylene dimethyl ethers (PODE, with the formula of CH3O-(CH2O)(n)-CH3), as a promising environmentally benign diesel fuel or additive with an enormous potential in the reduction of soot and NIC, emissions, can be efficiently synthesized from methanol derivatives such as dimethoxymethane (DMM) and trioxymethylene (TOM), which requests a proper catalyst of high performance. In this work, the catalytic performance of graphene oxide (GO) in the synthesis of PODEn as well as its relation to the catalyst structure was thoroughly investigated. The results indicate that GO is an excellent catalyst in the synthesis of PODEn from DMM and TOM; a TOM conversion of 94.6% and selectivity of 86.0% to PODE2-8 are achieved under mild reaction conditions, which is superior to the majority of the state-of-the-art catalysts. Meanwhile, the active species and characteristic layer structure of GO sheets catalytically responsible for PODEn formation were discriminated through selectively removing certain surface functional groups, thermally annealing at different temperatures, and carefully comparing with a series of model compounds. The results illustrate that the superior catalytic performance of GO in the PODEn synthesis should be ascribed to a synergy between the surface sulfonyl, hydroxyl and carboxyl groups present on the GO surface and the unique layered structure of GO sheets, wherein the surface sulfonyl groups act as the main active sites. The insights shown in this work are beneficial to a deep understanding on the catalytic principle of GO and development of efficient catalyst for the synthesis of PODEn.

Welcome to talk about 87-41-2, If you have any questions, you can contact Wang, RY; Wu, ZW; Li, ZK; Qin, ZF; Chen, CM; Zheng, ZF; Wang, GF; Fan, WB; Wang, JG or send Email.. HPLC of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Computed Properties of C8H6O2. Cimerman, R; Cibikova, M; Satrapinskyy, L; Hensel, K in [Cimerman, Richard; Cibikova, Maria; Hensel, Karol] Comenius Univ, Fac Math Phys & Informat, Dept Astron Phys Earth & Meteorol, Mlynska Dolina F2, Bratislava 84248, Slovakia; [Satrapinskyy, Leonid] Comenius Univ, Fac Math Phys & Informat, Dept Expt Phys, Mlynska Dolina F2, Bratislava 84248, Slovakia published The Effect of Packing Material Properties on Tars Removal by Plasma Catalysis in 2020, Cited 108. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Plasma catalysis has been utilized in many environmental applications for removal of various hydrocarbons including tars. The aim of this work was to study the tars removal process by atmospheric pressure DBD non-thermal plasma generated in combination with packing materials of various composition and catalytic activity (TiO2, Pt/gamma Al2O3, BaTiO3, gamma Al2O3, ZrO2, glass beads), dielectric constant (5-4000), shape (spherical and cylindrical pellets and beads), size (3-5 mm in diameter, 3-8 mm in length), and specific surface area (37-150 m(2)/g). Naphthalene was chosen as a model tar compound. The experiments were performed at a temperature of 100 degrees C and a naphthalene initial concentration of approx. 3000 ppm, i.e., under conditions that are usually less favorable to achieve high removal efficiencies. For a given specific input energy of 320 J/L, naphthalene removal efficiency followed a sequence: TiO2 > Pt/gamma Al2O3 > ZrO2 > gamma Al2O3 > glass beads > BaTiO3 > plasma only. The efficiency increased with the increasing specific surface area of a given packing material, while its shape and size were also found to be important. By-products of naphthalene decomposition were analyzed by means of FTIR spectrometry and surface of packing materials by SEM analysis.

Computed Properties of C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Cimerman, R; Cibikova, M; Satrapinskyy, L; Hensel, K or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Novel phosphate-solubilising bacteria isolated from sewage sludge and the mechanism of phosphate solubilisation WOS:000456175700046 published article about POLYCYCLIC AROMATIC-HYDROCARBONS; MICROBIAL COMMUNITY; MASS-SPECTROMETRY; PHOSPHORUS SOLUBILIZATION; FUSARIUM-WILT; SOIL; GROWTH; MICROORGANISMS; RHIZOSPHERE; PSEUDOMONAS in [Yu, Le-Yi; Huang, He-Biao; Wang, Xiao-Hong; Li, Sha; Feng, Nai-Xian; Zhao, Hai-Ming; Huang, Xian-Pei; Li, Yan-Wen; Li, Hui; Cai, Quan-Ying; Mo, Ce-Hui] Jinan Univ, Coll Life Sci & Technol, Guangdong Prov Res Ctr Environm Pollut Control &, Guangzhou 510632, Guangdong, Peoples R China in 2019, Cited 73. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Product Details of 87-41-2

A great amount of insoluble phosphate in agricultural soils is not available for crops. Three strains of bacteria (Bacillus megaterium YLYP1 Pseudumonas prosekii YLYP6 and Pseudomonas sp. YLYP29) isolated from activated sludge and soil could efficiently solubilise tricalcium phosphate. In particular, the novel strain P. prosekii YLYP6 produced 716 mg L-1 of available phosphate within 6 days under the optimal culture conditions [20 degrees C, pH 7.9, inoculum size of 0.5% (v:v)] determined by response surface methodology. P. prosekii YLYP6 demonstrated efficient phosphate solubilisation in response to broad variations in pH (5-9) and temperature (15-35 degrees C). The phosphate solubilisation curves of the strains fit well with a first-order kinetic model (R-2 > 0.939), with a halt-life of 1.51-5.94 d for 5.0 g L-1 calcium phosphate. Continuous culture experiments combined with scanning electron microscopic observations and gas chromatography-mass spectrometry analysis revealed that 2,3-dimethylfumaric acid, gluconic and N-butyl-tert-butylamine that were produced by P. prosekii YLYP6 were responsible for phosphate solubilisation by supplying H+ ions and organic anions. Efficient phosphate solubilisation in actual soil by P. prosekii YLYP6 demonstrated the strong application potential to reduce the use of chemical P fertilisers and the resulting agricultural nonpoint pollution. (C) 2018 Elsevier B.V. All rights reserved.

Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

SDS of cas: 87-41-2. Tseplin, EE; Tseplina, SN in [Tseplin, Evgeniy E.; Tseplina, Svetlana N.] Russian Acad Sci, Ufa Fed Res Ctr, Inst Mol & Crystal Phys, Prospekt Oktyabrya 151, Ufa 450075, Russia published Application of polar solvent effects in absorption spectra for determination of lowest electron-excited states of phthalide in 2019, Cited 37. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

The optical absorption spectra of phthalide in polar (methanol) and nonpolar (n-hexane) solvents are recorded. The electronic phthalide spectrum was calculated by TDDFT B3LYP/6-311 + G(d, p) using the polarisable continuum model. Based on an analysis of calculation data and the displacement of absorption bands in a polar solvent, it was established that the absorption bands of phthalide at energies of 3.51 and 3.96 eV correspond to singlet-triplet transitions to the T-1 and T-2 states, respectively.

Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.. SDS of cas: 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

I found the field of Plant Sciences; Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Synthesis of phthalide derivatives and evaluation on their antiplatelet aggregation and antioxidant activities published in 2020. Application In Synthesis of Isobenzofuran-1(3H)-one, Reprint Addresses Liang, S (corresponding author), Shanghai Univ Tradit Chinese Med, Innovat Res Inst Tradit Chinese Med, Shanghai 201203, Peoples R China.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

As part of our continuing efforts to discover structurally interesting bioactive phthalide derivatives, 23 of them with a structure incorporating thiophen or halogens were designed and synthesized, 17 of which are previously unreported. In vitro antiplatelet aggregation activity screening showed that 14b could significantly inhibit platelet aggregation induced by arachidonic acid, compared with edaravone (p < 0.01). Meanwhile, oxidative damage models using SH-SY5Y and PC12 cells induced by H2O2 were built to evaluate the antioxidant activity of the phthalide derivatives. In SH-SY5Y cells, compared with aspirin, 1a significantly increased the relative cell survival rate (p < 0.05). Compared with edaravone, 1a (p < 0.01) and 15b (p < 0.05) significantly increased the relative cell survival rate. In PC12 cells, 1a (p < 0.01), 15b (p < 0.01), and 12a (p < 0.05) remarkably increased the cell survival rate compared with edaravone. The present study identified lead structures to develop potential anti-ischemic stroke agents. Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Fang, X; Ma, Q; Zhang, KX; Yao, SY; Feng, Y; Jin, YS; Liang, S or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis WOS:000607189100011 published article about LATENT PATHOGENS; FUNGAL MELANINS; BIOSYNTHESIS; BOTRYOSPHAERIACEAE; TRICYCLAZOLE; IDENTIFICATION; PENETRATION; GROWTH; MELANIZATION; APPRESSORIA in [Airam Rangel-Montoya, Edelweiss; Hernandez-Martinez, Rufina] Ctr Invest Cient & Educ Super Ensenada CICESE, Dept Microbiol, Ensenada 22860, Baja California, Mexico; [Paolinelli, Marcos] Inst Nacl Tecnol Agr INTA, Estn Expt Agr Mendoza, San Martin 3853, RA-5534 Mendoza, Argentina; [Paolinelli, Marcos] Consejo Nacl Invest Cient & Tecn, Buenos Aires, DF, Argentina; [Rolshausen, Philippe] Univ Calif Riverside, Dept Bot & Plant Sci, Riverside, CA 92521 USA in 2020, Cited 69. Product Details of 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants. A common characteristic of this genus is the presence of melanin in conidia and mycelium. Melanin is produced by the oxidation of phenolic and/or indolic compounds. For some fungi, this pigment is an essential factor for pathogenicity. This study characterized the types and the roles of melanin produced by Lasiodiplodia gilanensis. Using specific melanin inhibitors, L. gilanensis was shown to synthesize DOPA-melanin, DHN-melanin, and pyomelanin. DOPA-melanin was shown to be involved in production of aerial mycelium and protection against enzymatic lysis and oxidative stress; DHN-melanin to be involved in ramification of mycelium when exposed to nutrient deficiency; and pyomelanin to be related with hyphae development. The fungus used tyrosine as a precursor of DOPA-melanin and as carbon and nitrogen sources, and produced melanin inside the piths of infected plants. Genes involved in melanin synthesis were conserved among the Botryosphaeriaceae, highlighting the importance of melanin in this family.

Welcome to talk about 87-41-2, If you have any questions, you can contact Rangel-Montoya, EA; Paolinelli, M; Rolshausen, P; Hernandez-Martinez, R or send Email.. Product Details of 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Category: benzofurans. Recently I am researching about POSSESSING 1,4-BENZODIOXAN MOIETY; BIOLOGICAL EVALUATION; MOLECULAR DOCKING; ANTIPROLIFERATIVE ACTIVITY; CARCINOMA-CELLS; ACID SYNTHESIS; CANCER; DESIGN; INHIBITORS; IDENTIFICATION, Saw an article supported by the . Published in MDPI in BASEL ,Authors: Stecoza, CE; Nitulescu, GM; Draghici, C; Caproiu, MT; Olaru, OT; Bostan, M; Mihaila, M. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

In order to develop novel chemotherapeutic agents with potent anticancer activities, a series of new 2,5-diaryl/heteroaryl-1,3,4-oxadiazoles were designed and synthesized. The structures of the new compounds were established using elemental analyses, IR and NMR spectral data. The compounds were evaluated for their anticancer potential on two standardized human cell lines, HT-29 (colon adenocarcinoma) and MDA-MB-231 (breast adenocarcinoma). Cytotoxicity was measured by MTS assay, while cell cycle arrest and apoptosis assays were conducted using a flow cytometer, the results showing that the cell line MDA-MB-231 is more sensitive to the compounds’ action. The results of the predictive studies using the PASS application and the structural similarity analysis indicated STAT3 and miR-21 as the most probable pharmacological targets for the new compounds. The promising effect of compound 3e, 2-[2-(phenylsulfanylmethyl)phenyl]-5-(4-pyridyl)-1,3,4-oxadiazole, especially on the MDA-MB-231 cell line motivates future studies to improve the anticancer profile and to reduce the toxicological risks. It is worth noting that 3e produced a low toxic effect in the D. magna 24 h assay and the predictive studies on rat acute toxicity suggest a low degree of toxic risks.

Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.. Category: benzofurans

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem