Category: benzofurans

An article SYNTHESIS AND EVALUATION OF THE ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF NOVEL DIBENZOTHIEPINES WOS:000600718700018 published article about DRUG; ANTIBACTERIAL; DISCOVERY in [Stecoza, Camelia Elena] Carol Davila Univ Med & Pharm, Fac Pharm, Dept Pharmaceut Chem, 6 Traian Vuia St, Bucharest 020956, Romania; [Draghici, Constantin; Caproiu, Miron Teodor] Costin D Nenitescu Ctr Organ Chem Romanian Acad, 202 B Splaiul Independentei, Bucharest 060023, Romania; [Pircalabioru, Gratiela Gradisteanu; Marutescu, Luminita] Univ Bucharest, Res Inst, Bucharest 60101, Romania in 2020, Cited 21. Application In Synthesis of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Considering the anti-infective potential of compounds containing the dibenzothiepine scaffold, we set out to obtain new compounds bearing this structure. The synthesized compounds were characterized by spectral studies and elemental analysis and screened for their microbiostatic/microbicidal and antibiofilm properties against reference and clinical microbial strains. The new compounds exhibited a broad spectrum of antimicrobial activity, which was more intensive for the S-oxidized compounds. Some of the compounds also inhibited the ability of the investigated strains to form biofilms on the inert substratum.

Welcome to talk about 87-41-2, If you have any questions, you can contact Stecoza, CE; Draghici, C; Caproiu, MT; Pircalabioru, GG; Marutescu, L or send Email.. Application In Synthesis of Isobenzofuran-1(3H)-one

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Formula: C8H6O2. Patil, A; Duggal, H; Bagul, KT; Kamble, S; Lokhande, P; Gacche, R; Meshram, R in [Patil, Avinash; Duggal, Harleen; Bagul, Kamini T.; Lokhande, Pradeep; Meshram, Rohan] Savitribai Phule Pune Univ, Dept Chem, Pune, Maharashtra, India; [Duggal, Harleen; Bagul, Kamini T.; Meshram, Rohan] Savitribai Phule Pune Univ, Bioinformat Ctr, Dept Biotechnol, Pune, Maharashtra, India; [Kamble, Sonali] Gramin Sci Vocat Coll, Vishnupuri, Nanded, India; [Gacche, Rajesh] Savitribai Phule Pune Univ, Dept Biotechnol, Pune, Maharashtra, India published Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study in 2020, Cited 73. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Objective: The study aims at the derivatization of Phthalides and synthesizes 3-arylaminophthalides & 3-indolyl-phthalides compounds, and evaluates their anti-tubercular and antioxidant activities. The study has also intended to employ the in silica methods for the identification of possible drug targets in Mycobacterium and evaluate the binding affinities of synthesized compounds. Methods: This report briefly explains the synthesis of phthalide derivatives using ammonium chloride. The synthesized compounds were characterized using spectral analysis. Resazurin Microtiter Assay (REMA) plate method was used to demonstrate the anti-mycobacterial activity of the synthesized compounds. An in-silico pharmacophore probing approach was used for target identification in Mycobacterium. The structural level interaction between the identified putative drug target and synthesized phthalides was studied using Lamarckian genetic algorithm-based software. Results and Discussion: In the present study, we report an effective, environmentally benign scheme for the synthesis of phthalide derivatives. Compounds 5c and 5d from the current series appear to possess good anti-mycobacterial activity. dCTP: deaminasedUTPase was identified as a putative drug target in Mycobacterium. The docking results clearly showed the interactive involvement of conserved residues of dCTP with the synthesized phthalide compounds. Conclusion: On the eve of evolving anti-TB drug resistance, the data on anti-tubercular and allied activities of the compounds in the present study demonstrates the enormous significance of these newly synthesized derivatives as possible candidate leads in the development of novel anti-tubercular agents. The docking results from the current report provide a structural rationale for the promising anti-tubercular activity demonstrated by 3-arylaminophthalides and 3-indolyl-phthalides compounds.

Welcome to talk about 87-41-2, If you have any questions, you can contact Patil, A; Duggal, H; Bagul, KT; Kamble, S; Lokhande, P; Gacche, R; Meshram, R or send Email.. Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Wang, J; Li, X; Cheng, JP in [Wang, Jie; Li, Xin; Cheng, Jin-Pei] Nankai Univ, State Key Lab Elementoorgan Chem, Collaborat Innovat Ctr Chem Sci & Engn, Coll Chem, Tianjin 300071, Peoples R China published Quinine-derived thiourea promoted enantioselective Michael addition reactions of 3-substituted phthalides to maleimides in 2019, Cited 44. Name: Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

A highly diastereoselective and enantioselective Michael addition/desymmetrization reaction of maleimides with prochiral 3- substituted phthalides catalyzed by quinine-derived bifunctional thiourea was realized. A broad range of the 3,3-disubstituted phthalides bearing vicinal quaternary-tertiary stereogenic centers were synthesized in moderate to good yields (up to 96%) with high diastereoselectivities (up to >19:1 dr) and enantioselectivities (up to 96:4 er).

Name: Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Das, UK; Janes, T; Kumar, A; Milstein, D in [Das, Uttam Kumar; Janes, Trevor; Kumar, Amit; Milstein, David] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel; [Kumar, Amit] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland published Manganese catalyzed selective hydrogenation of cyclic imides to diols and amines in 2020, Cited 43. HPLC of Formula: C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Herein we report the selective hydrogenation of cyclic imides to diols and amines, homogeneously catalyzed for the first time by a complex of an earth-abundant metal, a manganese pincer complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments.

HPLC of Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Das, UK; Janes, T; Kumar, A; Milstein, D or send Email.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Safety of Isobenzofuran-1(3H)-one. Authors Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN in ROYAL SOC CHEMISTRY published article about in [Rumyantsev, Andrey, V; Pichugov, Andrey, V; Bushkov, Nikolai S.; Aleshin, Dmitry Yu; Strelkova, Tatyana, V; Lependina, Olga L.; Zhizhko, Pavel A.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Rumyantsev, Andrey, V; Bushkov, Nikolai S.] Moscow MV Lomonosov State Univ, Dept Chem, Vorobevy Gory 1, Moscow 119991, Russia; [Pichugov, Andrey, V; Aleshin, Dmitry Yu] D Mendeleev Univ Chem Technol Russia, Higher Chem Coll, Miusskaya Sq 9, Moscow 125047, Russia in 2021, Cited 33. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

We report the first examples of direct imidation of lactones giving the corresponding cyclic imidates via oxo/imido heterometathesis with N-sulfinylamines catalysed by a well-defined silica-supported Ti imido complex.

Welcome to talk about 87-41-2, If you have any questions, you can contact Rumyantsev, AV; Pichugov, AV; Bushkov, NS; Aleshin, DY; Strelkova, TV; Lependina, OL; Zhizhko, PA; Zarubin, DN or send Email.. Safety of Isobenzofuran-1(3H)-one

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

HPLC of Formula: C8H6O2. In 2019 FITOTERAPIA published article about RESAZURIN in [Intaraudom, Chakapong; Bunbamrung, Nantiya; Dramae, Aibrohim; Boonruangprapa, Tanapong; Pittayakhajonwut, Pattama] Natl Sci & Technol Dev Agcy, Natl Ctr Genet Engn & Biotechnol BIOTEC, Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathum Thani, Thailand; [Punyain, Wikorn] Naresuan Univ, Fac Sci, Dept Chem, Phitsanulok 65000, Thailand in 2019, Cited 12. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Fourteen new compounds including thirteen drimane – phthalide derivatives (fendlerals A – C, fendlerins A – D, fendlerols A – B, fendleric acids A – C, fendlerinine G) and one terphenyl derivative (fendleryl E) along with eight known compounds, fendlerinine A, rickenyls C – D, fendleryls C – D, atromentin, tetramethyl atromentin, and ( +/- )-microsphaerophthalide F, were isolated from the wood fungus Hypoxylon fendleri BCC32408. Compared with the prior work, the results indicated the agitation effect on the production of bioactive drimane – phthalides. The chemical structures were determined based upon spectroscopic analyses and the absolute configurations were verified by comparison of the ECD spectral data with the calculated ECD spectra of the related compounds. Compounds 1-3 exhibited antimicrobial activity against Plasmodium falciparum (IC50 4.15-4.39 mu M), Colletotrichum capsici (MIC 6.25-12.5 mu g/mL), and Bacillus cereus (MIC 1.56-3.13 mu g/mL). All tested compounds displayed broad cytotoxicity against cancerous (MCF-7, KB, and NCI-H187) and non-cancerous (Vero) cells.

Welcome to talk about 87-41-2, If you have any questions, you can contact Intaraudom, C; Punyain, W; Bunbamrung, N; Dramae, A; Boonruangprapa, T; Pittayakhajonwut, P or send Email.. HPLC of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about INTRAMOLECULAR SPIROCYCLIZATION; MOLECULES; NANOSCOPY, Saw an article supported by the ETH ZurichETH Zurich [ETH-0216-1]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Halabi, EA; Pinotsi, D; Rivera-Fuentes, P. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. HPLC of Formula: C8H6O2

Photoswitchable molecules have multiple applications in the physical and life sciences because their properties can be modulated with light. Fluxional molecules, which undergo rapid degenerate rearrangements in the electronic ground state, also exhibit switching behavior. The stochastic nature of fluxional switching, however, has hampered its application in the development of functional molecules and materials. Here we combine photoswitching and fluxionality to develop a fluorophore that enables very long (>30 min) time-lapse single-molecule localization microscopy in living cells with minimal phototoxicity and no apparent photobleaching. These long time-lapse experiments allow us to track intracellular organelles with unprecedented spatiotemporal resolution, revealing new information of the three-dimensional compartmentalization of synaptic vesicle trafficking in live human neurons.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about ALLYLIC AMINES; ARYL IODIDES; POLYMERIZATION; POLYMERS; COMPLEX; ETHYLENE; CYCLOPOLYMERIZATION; COPOLYMERIZATION; POLYETHYLENES; ALKYLENE)S, Saw an article supported by the JSPS KAKENHIMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [JP15H03814]. Published in WILEY in HOBOKEN ,Authors: Tan, LY; Takeuchi, D; Osakada, K. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Product Details of 87-41-2

The Pd-catalyzed three-component coupling polycondensation of diiodoarenes, nonconjugated dienes, and carbonucleophiles afforded poly(arylene alkenylene)s with moderate molecular weight in good yield. The reaction involves Mizoroki-Heck coupling, olefin migration via chain walking, and addition of the carbonucleophile to the resulting pi-allylpalladium species. The polymerization with a slight excess of nucleophile with respect to diiodoarene also proceeded to give the polymer without significant decrease in molecular weight in spite of the nonstoichiometric mixture of the monomers. The Pd-catalyzed three-component coupling polycondensation of diiodoarenes, nonconjugated dienes, and diimide also proceeded. The base used in the reaction is critical for yield and molecular weight of the product. The reaction using NaHCO3 afforded the product with low solubility, which can be explained by the high molecular weight of the polymer and/or the strong interaction of the electron donating dimethoxyphenylene groups and electron accepting diimide groups in the polymer. (c) 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019

Welcome to talk about 87-41-2, If you have any questions, you can contact Tan, LY; Takeuchi, D; Osakada, K or send Email.. Product Details of 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Combined targeted and untargeted profiling of volatile aroma compounds with comprehensive two-dimensional gas chromatography for differentiation of virgin olive oils according to variety and geographical origin WOS:000443253200052 published article about SOLID-PHASE MICROEXTRACTION; LIPOXYGENASE PATHWAY; QUALITY; CULTIVARS; CLASSIFICATION; HYDROCARBONS; TRACEABILITY; TEMPERATURE; FLAVOR; ODOR in [Lukic, Igor; Horvat, Ivana] Inst Agr & Tourism, K Huguesa 8, Porec 52440, Croatia; [Lukic, Igor] Ctr Excellence Biodivers & Mol Plant Breeding, Svetosimunska 25, Zagreb 10000, Croatia; [Carlin, Silvia; Vrhovsek, Urska] Fdn Edmund Mach FEM, Res & Innovat Ctr, Dept Food Qual & Nutr, Via E Mach 1, I-38010 San Michele All Adige, TN, Italy; [Carlin, Silvia] Univ Udine, Dept Agr Food Environm & Anim Sci, Via Sci 208, I-33100 Udine, Italy in 2019, Cited 35. COA of Formula: C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry (GC x GC-TOF-MS) was combined with conventional mono-dimensional GC-MS to differentiate Croatian virgin olive oils (VOO) according to variety and geographical origin, based on the profile of volatile aroma compounds isolated by HS-SPME. More than 1000 compounds were detected after untargeted profiling and 256 were identified or tentatively identified, providing one of the most detailed profiles of volatile aroma compounds in VOO up to date. Among them, 131 volatile compounds were significantly different across monovarietal VOOs, while 60 were found useful for the discrimination according to geographical origin. Many major lipoxygenase and minor non-lipoxygenase-generated compounds were shown to have discriminating ability with respect to both factors. Multivariate statistical analysis extracted twenty-one volatile markers with the highest discriminant power for varietal differentiation. The approach reported may have practical application in better understanding, defining, managing, and communicating the varietal or geographical typicity of monovarietal VOOs.

Welcome to talk about 87-41-2, If you have any questions, you can contact Lukic, I; Carlin, S; Horvat, I; Vrhovsek, U or send Email.. COA of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about CONDITION PHTHALIMIDINE SYNTHESIS; DUAL SYNTHETIC AUXILIARIES; 1,2,3-1H-BENZOTRIAZOLE; 2-MERCAPTOETHANOL; ISOINDOLINONES; MECHANISM, Saw an article supported by the . Recommanded Product: 87-41-2. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Takahashi, I; Nishiwaki, Y; Saitoh, K; Matsunaga, T; Aratake, A; Morita, T; Hosoi, S. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Direct condensation between phthalide and a primary amine in the presence of Lewis acid was achieved for the first time in organic solvent-diluted reaction systems catalyzed by GaCl3. The peripheral aspects of this reaction is discussed.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem