Simple exploration of Ethyl 5-nitrobenzofuran-2-carboxylate

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Application of 69604-00-8, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 69604-00-8, molcular formula is C11H9NO5, introducing its new discovery.

The invention belongs to the field of organic synthesis, in particular discloses a nitro-aromatic hydrocarbon and boric acid compound coupling-synthesizing sulfonamide compounds of the method, including: in the organic solvent, in order to pyrosulfites is SO2 Source, heating up coupling reaction, and then after treatment to obtain a sulfonamide compounds; the method of the invention is simple to operate, without nitrogen protection, air can be carried out, nitro aromatic hydrocarbon and boric acid compound sources are abundant, the cost is relatively low, the reaction yield is high, the substrate has wide applicability, metal-free residue. The method of the invention can be used for synthesizing a series of sulfonamide compounds, synthetic compounds in the pesticide, medicine and other field have wide application value. (by machine translation)

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3848O – PubChem

A new application about Ethyl 5-nitrobenzofuran-2-carboxylate

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Chemistry is traditionally divided into organic and inorganic chemistry. Product Details of 69604-00-8, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 69604-00-8

The invention relates to a […] intermediate synthesis method, in order to 6 – nitro coumarin as the starting the raw materials, through ring-opening, the ring in the molecule, esterification, reduction, paipai qin link other steps, to obtain key […] middle style I compound 5 – (1 – piperazinyl) – 2 – benzofuran – 2 – carboxylic acid ethyl ester. The invention synthetic route is simple, the target product yield is relatively high, and is suitable for industrial scale production. (by machine translation)

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3851O – PubChem

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Application of 69604-00-8, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.69604-00-8, Name is Ethyl 5-nitrobenzofuran-2-carboxylate, molecular formula is C11H9NO5. In a article,once mentioned of 69604-00-8

Compounds of formula (I) are disclosed which are vitronectin receptor antagonists useful in the treatment of osteoporosis. 1

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3852O – PubChem

Archives for Chemistry Experiments of Ethyl 5-nitrobenzofuran-2-carboxylate

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A series of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides were prepared, using an efficient three- to five-step synthesis, and evaluated for their inhibitory activity against human cytochrome P450C24A1 (CYP24A1) hydroxylase. Inhibition ranged from IC50 0.3-72 muM compared with the standard ketoconazole IC50 0.52 muM, with the styryl derivative (11c) displaying enhanced activity (IC50 = 0.3 muM) compared with the standard, providing a useful preliminary lead for drug development.

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Benzofuran – Wikipedia,
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Targeted radionuclide therapy using radioiodinated compounds with a specific affinity for melanoma tissue is a promising treatment for disseminated melanoma, but the candidate with the ideal kinetic profile remains to be discovered. Targeted radionuclide therapy concentrates the effects on tumor cells, thereby increasing the efficacy and decreasing the morbidity of radiotherapy. In this context, analogues of N-(2-diethylaminoethyl)-4- iodobenzamide (BZA) are of interest. Various (hetero)aromatic analogues 5 of BZA were synthesized and radioiodinated with 125I, and their biodistribution in melanoma-bearing mice was studied after i.v. administration. Most [125I]5-labeled compounds appeared to bind specifically and with moderate-to-high affinity to melanoma tumor. Two compounds, 5h and 5k, stood out with high specific and long-lasting uptake in the tumor, with a 7- and 16-fold higher value than BZA at 72 h, respectively, and kinetic profiles that makes them promising agents for internal targeted radionuclide therapy of melanoma.

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Benzofuran – Wikipedia,
Benzofuran | C8H3866O – PubChem

Some scientific research about Ethyl 5-nitrobenzofuran-2-carboxylate

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A compound of Formula (I) or a salt, solvate and chemically protected form thereof, wherein: R5 is an optionally substituted C5-20 aryl or C4-20 alkyl group; A is selected from the group consisting of Formulae (Ai), (Aii), (Aiii) D is selected from Formulae (Di), (Dii), (Diii), (Div), (Dv) B is selected from the group consisting of Formulae (Bi), (Bii), (Biii), (Biv) (Bv).

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3859O – PubChem

Extended knowledge of Ethyl 5-nitrobenzofuran-2-carboxylate

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 69604-00-8 is helpful to your research. Application of 69604-00-8

Application of 69604-00-8, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 69604-00-8, molcular formula is C11H9NO5, introducing its new discovery.

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3847O – PubChem

Discovery of Ethyl 5-nitrobenzofuran-2-carboxylate

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Application of 69604-00-8, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 69604-00-8, Name is Ethyl 5-nitrobenzofuran-2-carboxylate, molecular formula is C11H9NO5. In a Patent,once mentioned of 69604-00-8

The present invention provides a pyrimidine heterocyclic compound, pyrimidine heterocyclic compound salt and preparation method and application, the present invention provides compounds of formula (I) pyrimidine heterocyclic compound, through the selection of a particular Rq, so that the obtained compound as the treatment or prevention of anti-HIV virus drugs, not only has very good drug resistance and long half-life, but also the compound active high, low in toxicity and high stability. (by machine translation)

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Benzofuran – Wikipedia,
Benzofuran | C8H3862O – PubChem

Properties and Exciting Facts About 69604-00-8

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The disclosure relates to pyrido[2,3-d]pyrimidone compounds, to the preparation thereof and to the therapeutic use thereof, wherein said compounds are of general formula (I): in the form of a base or of an addition salt with an acid which is pharmaceutically acceptable, in the form of hydrates or of solvates, and also in the form of enantiomers, diastereoisomers and a mixture thereof. The disclosure also relates to processes for preparing said compounds, to pharmaceutical compositions containing a compound of general formula (I), and to the therapeutic use of said compounds and compositions.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3860O – PubChem

More research is needed about Ethyl 5-nitrobenzofuran-2-carboxylate

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Reference of 69604-00-8, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 69604-00-8, Ethyl 5-nitrobenzofuran-2-carboxylate, introducing its new discovery.

An irreversible ligand (7) has been prepared based on the selective I2 ligand 2-BFI. Compound 7 displayed high affinity and selectivity for I2-sites and has been shown to irreversibly bind to these sites in rat brain. Compound 7 should, therefore, prove an invaluable tool for the further elucidation of I2-site function. (C) 2000 Elsevier Science Ltd. All rights reserved.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3867O – PubChem