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A 5,6,7,8-tetrafluoroanthraquinone derivative represented by the general formula I: STR1 wherein R1 and R2 independently stand for –OH or STR2 (where R3 and R4 independently stand for hydrogen an alkyl of 1 to 4 carbon atoms or a phenyl) and X and Y independently hydrogen atom or a halogen atom.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3685O – PubChem

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The invention discloses a method for detecting cysteine fluorescence probe and its preparation method and method of use. This invention utilizes the phthalimide framed classical intramolecular charge transfer (ICT) system, and a benzene ring is introduced into the remaining positions in the four atomic fluorine, make it more biological stability and optical stability. The probe itself is a fluorine atom inhibit the ICT effect without fluorescence emission, but under the conditions when there is a cysteine, fluorine atom is cysteine substituted, and then make its inhibiting effect disappears, the probe molecule emits strong fluorescence. The invention provides N – butyl four-phthalic acid imide dye “on – off” type cysteine probe to cysteine solution has a good response, can be realized to the sample of the trace in the cysteine of the sensitive quantitative detection, has simple operation, low cost, and sensitive response, easy popularization and application and the like. (by machine translation)

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3679O – PubChem

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A pyridine ring-containing benzoxazinone derivative or a pharmaceutically acceptable salt or tautomer thereof represented by general formula (1): (wherein R1 to R6 and n are as defined in the description) has excellent inhibitory activity against a protease. Thus, the benzoxazinone derivative or a pharmaceutically acceptable salt thereof is useful as an active ingredient for a therapeutic agent for virus infections, particularly herpes virus infections.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3698O – PubChem

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Electric Literature of 652-12-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.652-12-0, Name is Tetrafluorophthalic anhydride, molecular formula is C8F4O3. In a Article,once mentioned of 652-12-0

A formal [5 – 1 + 2] annulation for the preparation of substituted alpha-pyrones is reported. The reaction involves the decarbonylative coupling of substituted maleic anhydrides with internal alkynes in the presence of a rhodium(III) catalyst and a copper(II) salt, affording tri- and tetrasubstituted alpha-pyrones. the Partner Organisations 2014.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3738O – PubChem

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652-12-0, Name is Tetrafluorophthalic anhydride, belongs to benzofurans compound, is a common compound. Computed Properties of C8F4O3In an article, once mentioned the new application about 652-12-0.

A series of zinc(II) porphyrinimide dyads (ZP-Im), in which an electron donating ZP moiety is directly connected to an electron accepting imide moiety in the meso position, have been prepared for the examination of energy gap dependence of intramolecular electron transfer reactions with large electronic coupling. The nearly perpendicular conformation of the imide moiety towards the porphyrin plane has been revealed by X-ray crystal structures. The energy gap for charge separation, 1Zp*-Im ? ZP+ – Im-, is varied by changing the electron accepting imide moiety to cover a range of about 0.8 eV in DMF. Definitive evidence for electron transfer has been obtained in three solvents (toluene, THF, and DMF) through picosecond-femtosecond transient absorption studies, which have allowed us to determine the rates of photoinduced charge separation, 1ZP*-Im?ZP+-Im-, and subsequent thermal charge recombination ZP+-Im-? ZP-Im. The free-energy gap dependence (energy gap law) has been probed from the normal to the nearly top region for the charge separation rate alone, and only the inverted region for the charge recombination rate. Although both of the energy gap dependencies can be approximately reproduced by means of the simplified semiclassical equation, when we take into consideration the effect of the high frequency vibrations replaced by one mode of averaged frequency, many features, including the effects of solvent polarity and the electron tunneling matrix element on the energy gap law, differ considerably from those of the previously studied porphyrin – quinone systems, which have weaker interchromophore electronic interactions.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3780O – PubChem

More research is needed about Tetrafluorophthalic anhydride

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New highly fluorinated aromatic polyimides based on hexafluoro-2,4- toluenediamine and commercially available dianhydrides (6FDA and ODPA) were synthesized by one-pot high temperature polycondensation in benzoic acid melt. Owing to the CF3 group and fluorine atoms in the meta-linked phenylenediamine fragment, these polyimides combine good solubility in organic solvents including such a low boiling point solvent as chloroform with high glass transition temperatures (330-345 C), thermal and thermooxidative stability (T5 is >500 C). The highly fluorinated polyimide films (hydrogen content is ?1%) exhibit good dielectric properties and low water absorption as well as excellent optical transparency in the UV-vis region (cut-off wavelength is 311 nm for 6FDA-based and 357 nm for ODPA-based polyimides), which is very important for optoelectronic materials.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3764O – PubChem

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[PROBLEM TO BE SOLVED]: To provide a method for producing aromatic fluorine compound (for example, pentafluorobenzonitrile) in a high yield by exchange reaction of aryl halide (for example, pentachlorobenzonitrilel) with fluorination reagent (for example, potassium fluoride).[SOLUTION]: The aryl halide is supplied to the reaction as a particle within the range of mean particle diameter 20-200 micro meter.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3786O – PubChem

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Thiadiazolobenzoimidazole (TBI) acceptor was designed in order to increase the electron-withdrawing ability of 2,1,3-benzothiadiazole (BT). The key feature of TBI is the three electron deficient imine groups, rendering it a stronger acceptor than BT. Three TBI-containing compounds TBI-a to TBI-c were synthesized by reaction between 5,6-diamino-2,1,3-benzothiadiazole analogue and the corresponding anhydride and exhibit maximum absorption at 600 nm. The band gaps of TBI-a to TBI-c are in between that of BT-containing compounds and benzo(1,2-c:4,5-c?)bis[1,2,5]thiadiazole-containing compounds, ranging from 1.60 to 1.88 eV, which make them potentially useful for organic solar cell application. Moreover, all the compounds are electrochromic and become absorbing at the telecommunication wavelengths upon electrochemical switching.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3732O – PubChem

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This paper describes the synthesis of N-pyridinyl(alkyl)phthalimides related to N-phenyl-4,5,6,7-tetrafluorophthalimides known to be inhibitors of tumour necrosis factor-alpha (TNFalpha) production. Pharmacomodulation at the phthalimidic nitrogen led to the selection of two pharmacophoric fragments (2,4-lutidinyl and beta-picolyl), allowing significant inhibition of TNFalpha production (compounds 12 and 17). Variation of the substituents linked to the homocycle of their phthalimide scaffold indicated that high (TNFalpha production) inhibitory potency could be achieved, notably by 5-fluoro, 4- or 5-nitro, 5-amino and especially tetrafluoro substitution. The most active compound, N-(pyridin-3-ylmethyl)-4,5,6,7-tetrafluorophthalimide (32) (84% inhibition at 10 muM), also produced an anti-oedematous effect in the PMA-induced mouse-ear swelling test. Although less active than dexamethasone, it exerted a marked reduction in ear thickness after oral administration (63% vs. 85% for dexamethasone at 0.2 mM kg-1) and remained efficient after topical application (46% vs. 96% for the dexamethasone). It also induced potent inhibition in the rat carrageenan foot oedema test with an ID50 (0.14 muM kg-1) comparable with that of N-(2,6-diisopropylphenyl)phthalimide (4) (0.15 muM kg-1).

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3715O – PubChem

Discovery of Tetrafluorophthalic anhydride

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Quality Control of Tetrafluorophthalic anhydride, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 652-12-0, name is Tetrafluorophthalic anhydride. In an article,Which mentioned a new discovery about 652-12-0

A process for producing tetrafluorophthalic anhydride, which comprises chlorinating tetrachlorophthalic anhydride to obtain 3,3,4,5,6,7-hexachloro-1-[3H]-isobenzofuranone, then fluorinating it to obtain 3,4,5,6-tetrafluorophthaloyldifluoride and/or 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone, and further reacting the tetrafluorophthalolyldifluoride and/or the hexafluoro-1-[3H]-isobenzofuranone with an inorganic base or an organic acid to obtain tetrafluorophthalic anhydride.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3696O – PubChem