Category: 6296-53-3

In an article, author is Li, Wenxi, once mentioned the application of 6296-53-3, Product Details of 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, molecular formula is C10H7NO4, molecular weight is 205.1669, MDL number is MFCD00453138, category is benzofurans. Now introduce a scientific discovery about this category.

Neoveratrol A-D: Four new arylbenzofurans from Veratrum nigrum

Four new arylbenzofurans, 2-(3′,5′-dimethoxy) phenyl-6-hydroxy-7-methoxy benzofuran (1, Neoveratrol A), 2-(3′-O-beta-D-glucosyl-5′-hydroxy) phenyl-4,6-dimethoxy benzofuran (2, Neoveratrol B), 2-(3′,5′-dimethoxy) phenyl-4-O-beta-D-glucosyl-6-hyroxy benzofuran (3, Neoveratrol C), 2-(3′,5′-dimethoxy) phenyl-6-hydroxy-7-O-beta-D-glucosyl benzofuran (4, Neoveratrol D), together with nine known ones (5-13) were isolated from the dried root and rhizome of a Traditional Mongolian medicinal herb Veratrum nigrum. The structures were elucidated by various spectroscopic methods including UV, IR, NMR and HR-MS. Among these compounds, 1-3, 5, 7-9 and 11-13 showed significant inhibitory effects on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells at the concentration ranging from 50.0-200.0 mu M. Compound 1 exhibited moderate activity against HepG2 and HCT-15. In addition, compound 5 and 6 showed inhibitory activities against human tumor cell lines HepG2, HCT-15, A549, MDA-MB-231 and SH-SY5Y with IC50 range of 40-100 mu M.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide. In a document, author is Mydlova, L., introducing its new discovery. HPLC of Formula: C10H7NO4.

Selected molecules based on (-1-cyanovinyl)benzonitrile as new materials for NLO applications – Experimental and computational studies

The (Z)-4-(1-cyano-2-(5-methylfuran-2-yl)vinyl)benzonitrile molecule named as A, the (Z)-4-(2-(benzofuran-2-yl)-1-cyanovinyl)benzonitrile named as B and the (2)-4-(2-(4-(9H-carbazol-9-yl)phenyl)-1-cyanovinyl) benzonitrile molecule named as C were investigated using experimental technique and computational models. Their linear and nonlinear optical parameters were measured and the adequate hyperpolarizabilities were calculated applying the HE and NT methods. The appropriate calculation method was chosen by comparing the experimental and theoretical UV-vis absorption spectra. The influence of the dipole moment and effect of twist angle between donor-acceptor group and their intermolecular interaction at the linear and nonlinear optical properties were discussed. Was demonstrated that the (Z)-4-(2-(4-(9H-carbazol-9-yl)phenyl)-1-cyanovinyl) benzonitrile incorporated into PMMA matrix possess the largest NUJ responses (SHG and THG efficiency). (C) 2020 Elsevier B.V. All rights reserved.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 6296-53-3 help many people in the next few years. HPLC of Formula: C10H7NO4.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, molecular formula is C10H7NO4, belongs to benzofurans compound, is a common compound. In a patnet, author is Youssif, Bahaa G. M., once mentioned the new application about 6296-53-3, SDS of cas: 6296-53-3.

5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents

Cannabinoids as THC and the CB1 allosteric modulator CBD were reported to have antiproliferative activities with no reports for other CB1 allosteric modulators as the 5-chloroindole-2-carboxamide derivatives and their furan congeners. Based on the antiproliferative activity of two 5-chlorobenzofuran-2-carboxamide allosteric CB1 modulators, a series of novel derivatives was designed and synthesized. The synthesized compounds were tested in a cell viability assay using human mammary gland epithelial cell line (MCF-10A) where all the compounds exhibited no cytotoxic effects and more than 85% cell viability at a concentration of 50 mu M. Some derivatives showed good antiproliferative activities against tumor cells as compounds 8,15, 21 and 22. The most active compound 15 showed equipotent activity to doxorubicin. Compounds 7, 9, 15, 16, 21 and 22 increased the level of active caspase 3 by 4-8 folds, compared to the control cells in MCF-7 cell line and doxorubicin as a reference drug. Compounds 15 and 21, the most activecaspase-3 inducers, increase the levels of caspase 8 and 9 indicating activation of both intrinsic and extrinsic pathways and showed potent induction of Bax, down-regulation of Bcl-2 protein levels and over-expression of Cytochrome C levels in MCF-7 cell lines. Compound 15 exhibited cell cycle arrest at the Pre-G1 and G2/M phases in the cell cycle analysis of MCF-7 cell line. The drug Likeness profile of the synthesized compounds showed that all the compounds were predicted to have high oral absorption complying with different pharmacokinetics filters. (C) 2019 Elsevier Masson SAS. All rights reserved.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 6296-53-3. The above is the message from the blog manager. SDS of cas: 6296-53-3.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In an article, author is Khemalapure, Seema S., once mentioned the application of 6296-53-3, COA of Formula: C10H7NO4, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, molecular formula is C10H7NO4, molecular weight is 205.1669, MDL number is MFCD00453138, category is benzofurans. Now introduce a scientific discovery about this category.

Spectroscopic (FT-IR, FT-Raman, NMR and UV-Vis), ELF, LOL, NBO, and Fukui function investigations on (5-bromo-benzofuran-3-yl)-acetic acid hydrazide (5BBAH): Experimental and theoretical approach

Experimental and theoretical spectroscopic studies were performed for the (5-Bromo-benzofuran-3-yl)-acetic acid hydrazide (5BBAH) molecule. The research work was performed in two levels. In the first level, experimental FT-IR, FT-Raman, NMR (H-1, C-13) chemical shift and UV-Vis spectral data were recorded. In the next level the theoretical computations have been conducted from DFT/B3LYP/6-311++G (d, p) basis level. Initially, the theoretical geometrical parameters were obtained and matched with related experimental parameters. The computed FT-IR and FT-Raman frequencies were collected from same basis level and matched with experimental data. The vibrational assignments were achieved on the PED of individual vibrational modes. The theoretical NMR chemical shifts were compared with recorded experimental data. Theoretical (TD-DFT) and experimental UV-Vis absorption wavelengths (lambda) were compared with each other. In addition, FMO, NBO, MEP, ELF, LOL and Fukui function analysis were performed. (C) 2019 Published by Elsevier B.V.

If you are interested in 6296-53-3, you can contact me at any time and look forward to more communication. COA of Formula: C10H7NO4.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Synthetic Route of 6296-53-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, SMILES is CC(NC1=CC=CC(C(O2)=O)=C1C2=O)=O, belongs to benzofurans compound. In a article, author is Sun, Weipeng, introduce new discover of the category.

Bis(benzofurano)pyrrole and hybrid thienopyrrole derivatives for organic thin-film transistors

To develop new element blocks based on thienopyrroles (DTP) units, bis(benzofurano)pyrrole and hybrid thienopyrrole derivatives were synthesized by Buchwald-Hartwing amination methods. Optical absorption, cyclic voltammetry (CV), single-crystal X-ray diffraction analyses and organic thin-film transistor (OTFT) were employed to investigate the structure-activity relationships of the resulting pyrrole derivatives. It was found that the introduction of a benzofuran unit enhances the planarity and conjugation of heteroacenes leading to strong molecular aggregation and denser pi-pi stacking, resulting in better charge transport properties with the hole mobility of 0.025 cm(2)V(-1)s(-1) for the OTFTs.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, SMILES is CC(NC1=CC=CC(C(O2)=O)=C1C2=O)=O, belongs to benzofurans compound. In a document, author is Shigeno, Masanori, introduce the new discover, Recommanded Product: N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide.

Double-Carboxylation of Two C-H Bonds in 2-Alkylheteroarenes Using LiO-t-Bu/CsF

We describe the double-carboxylation of two C-H bonds (i.e., at the benzylic and the beta-positions) in 2-alkylheteroarenes using a combination of LiO-t-Bu and CsF. A diverse range of substrates, namely benzothiophene, thiophene, benzofuran, furan, and indole derivatives, are efficiently converted into the doubly carboxylated products. A variety of functionalities (i.e., methyl, methoxy, halogen, cyano, ester, ketone, and amide moieties) are well tolerated.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 6296-53-3 is helpful to your research. Recommanded Product: N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Formula: C10H7NO4, 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, SMILES is CC(NC1=CC=CC(C(O2)=O)=C1C2=O)=O, in an article , author is Mo, Lingchao, once mentioned of 6296-53-3.

New negative dielectric anisotropy liquid crystals based on benzofuran core

In this paper, new liquid crystal compounds with negative dielectric anisotropy were synthesised by regulating the substituents on the benzofuran ring. Their structures were confirmed by(1)H-nuclear magnetic resonance,(CNMR)-C-13 and mass spectra. The effects of substituent on the properties of liquid crystals were investigated. Compared with the reference compounds, the compounds with 5-ethoxy-6,7-difluorobenzofuran ring exhibit higher clearing points as well as the tendency of expansion of SmA phase range. The density functional theory calculation results reveal that the 6-ethoxy-7-fluorobenzofuran-based compound has smaller aspect ratio than that of the 5-ethoxy-6,7-difluorobenzofuran-based compound, which results in the diminish of the mesophase. Although the dielectric anisotropy of the 5-ethoxy-6,7-difluorobenzofuran-based compound is slightly lower than that of the reference compound, it has both the largest perpendicular and parallel dielectric constant.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 6296-53-3, you can contact me at any time and look forward to more communication. Formula: C10H7NO4.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, SMILES is CC(NC1=CC=CC(C(O2)=O)=C1C2=O)=O, belongs to benzofurans compound. In a document, author is Li, Xiaohui, introduce the new discover, Category: benzofurans.

Expanded benzofuran-decorated twistacene derivatives: synthesis, characterization and single-component white electroluminescence

Two novel phenanthro[9,10-b]benzofuran and pyreno[4,5-b]benzofuran modified twistacene derivatives, 9 and 10, have been successfully synthesized via Suzuki coupling and then characterized. The photophysical properties were examined and DFT calculations were carried out in a comparative manner, and both molecules emitted strong blue light in organic solvents and in the solid state. Impressively, fabricated electroluminescent devices based on these single emitters radiate pure white light.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 6296-53-3 is helpful to your research. Category: benzofurans.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Synthetic Route of 6296-53-3, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, SMILES is CC(NC1=CC=CC(C(O2)=O)=C1C2=O)=O, belongs to benzofurans compound. In a article, author is Chen, Hui, introduce new discover of the category.

Site-selective remote C(sp(3))-H heteroarylation of amides via organic photoredox catalysis

Radical translocation processes triggered by nitrogen-centered radicals (NCRs), such as 1,5-hydrogen atom transfers (1,5-HAT), demonstrated by the well-established Hofmann-Loffler-Freytag (HLF) reaction, provide an attractive approach for the controllable and selective functionalization of remote inert C(sp(3))-H bonds. Here we report an amidyl radical-triggered site-selective remote C(sp(3))-H heteroarylation of amides under organic photoredox conditions. This approach provides a mild and highly regioselective reaction affording remote C(sp(3))-H heteroarylated amides at room temperature under transition-metal free, weakly basic, and redox-neutral conditions. Non-prefunctionalized heteroarenes, such as purines, thiazolopyridines, benzoxazole, benzothiazoles, benzothiophene, benzofuran, thiazoles and quinoxalines, can be alkylated directly. Sequential and orthogonal C-H functionalization of different heteroarenes by taking advantage pH value or polarity of radicals has also been achieved. DFT calculations explain and can predict the site-selectivity and reactivity of this reaction. This strategy expands the scope of the Minisci reaction and serves as its alternative and potential complement.

Synthetic Route of 6296-53-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 6296-53-3 is helpful to your research.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, 6296-53-3, Name is N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, molecular formula is C10H7NO4, belongs to benzofurans compound. In a document, author is Ryabukhin, Dmitry S., introduce the new discover.

One-pot propargylation and Claisen-type rearrangement for natural lignans matairesinol and alpha-conidendrin

Improved methods for one-pot propargylation and Claisen rearrangement have been devised for natural lignans – matairesinol and alpha-conidendrin. The rearrangement was regiospecific, yielding only 2-methylbenzofuran derivatives.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 6296-53-3. Name: N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem