Category: 596-01-0

Gustafsson, Charley published the artcileSpectrophotometric measurements on α-naphtholphthalein, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Suomen Kemistiseuran Tiedonantoja (1934), 17-23, database is CAplus.

α-Naphtholphthalein prepared according to Schulenberg (cf. C. A. 15, 80) was examined in the same way as the Sörensen-Palitsch preparation (cf. preceding abstract). The secondary and primary dissociation constants were, resp., 8.9 × 10^-8 and 5.5 × 10^-5. The secondary ion is blue in both cases, but the primary is orange-red for the former and yellow for the latter.

Suomen Kemistiseuran Tiedonantoja published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Delcourt, R. published the artcileElectrophoretic behavior of phthaleins alone and in the presence of proteins, Quality Control of 596-01-0, the publication is Protides of the Biological Fluids (1959), 119-26, database is CAplus.

cf. C.A. 53, 5370g. The mobility of 16 phthalein dyes and their binding of human serum albumin was studied by paper electrophoresis at pH 8.6. By considering phenolphthalein as the simplest member of the series, mobility is diminished by methylation of the phenol moiety; sulfonation augments mobility without suppressing the effect of methylation, while halogenation suppresses the influence of methylation. For the formation of complexes with albumin, the presence of a halogen atom in the phthalein is essential. Affinity of halogenated phthaleins for proteins depends on the nature of the halogen (Cl < Br < I). Thus, iodophthalein is more firmly attached to the protein and is able to displace bromo- and chloro-phthalein from their protein complexes. It was not possible to determine which free groups on the protein are involved in this binding.

Protides of the Biological Fluids published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Quality Control of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Buch, Kurt published the artcileColor and acid characteristics of α-naphtholphthalein, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Suomen Kemistiseuran Tiedonantoja (1934), 6-17, database is CAplus.

Spectrophotometric measurements were made in alk., acid and borax buffer solutions on α-naphtholphthalein prepared according to Sörensen and Palitsch (C. A. 4, 1956). In 0.1% HCl it was nearly colorless at 0.007 g./l. The secondary ion shows absorption for wave length 649 μ, and both primary and secondary ions for 496 μ. The relative concentrations can be calculated from the extinction coefficients for these wave lengths. In this way the secondary dissociation constant is found to be 0.99 × 10^-8, and the primary 5.5 × 10^-6.

Suomen Kemistiseuran Tiedonantoja published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Buch, Kurt published the artcileThe influence of temperature on pit determinations with color indicators, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Suomen Kemistiseuran Tiedonantoja (1930), 2, database is CAplus.

The buffer solution should preferably be brought to the temperature of sea water in situ but if Walbum’s correction tables are used this cannot be under 10°. The p_H of a sample at t° is the p_H at the buffer t + α(t_a – t_b). α from Walbum’s table: for α-naphthophthalein -0.0084, phenolphthalein -0.01, phenol red 0.01 and cresol red -0.0053. If the temperature has changed during the colorimetric readings also add α'(t_a – t_a), α’ being 0.006 for α-naphthophthalein and 0.004 for phenol and cresol red. Phenolplithalein requires no correction.

Suomen Kemistiseuran Tiedonantoja published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Buch, Kurt published the artcileThe influence of temperature on pit determinations with color indicators, Quality Control of 596-01-0, the publication is Beret. 18th Skand. Naturforskermode (Copenhagen) (1929), 229-32, database is CAplus.

The buffer solution should preferably be brought to the temperature of sea water in situ but if Walbum’s correction tables are used this cannot be under 10°. The p_H of a sample at t° is the p_H at the buffer t + α(t_a -t_b). α from Walbum’s table: for α-naphthophthalein -0.0084, phenolphthalein -0.01, phenol red 0.01 and cresol red -0.0053. If the temperature has changed during the colorimetric readings also add α'(t’_a – t_a), α’ being 0.006 for α-naphthophthalein and 0.004 for phenol and cresol red. Phenolplithalein requires no correction.

Beret. 18th Skand. Naturforskermode (Copenhagen) published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Quality Control of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Aulin-Erdtman, Gunhild published the artcileValue of indicators for the determination of the acid number of tall oil, SDS of cas: 596-01-0, the publication is Svensk Papperstidning (1942), 333-5, database is CAplus.

The suitability of α-naphtholphthalein and Nile blue as indicators for the determination of the acid number of tall oil was investigated by means of potentiometric titrations on alc. solutions of model substances (oleic acid and purified resin acids) as well as of a distilled tall oil, in the presence of these indicators. Both indicators proved to be suitable but Nile blue could be used only if the solution contained less than 10% of water, because the color of this indicator in the range of the end point depends upon its water content. When α-naphtholphthalein is used, the end point should be taken at a dark-green color; Nile blue requires a shade between red and scarlet. Where greater accuracy is demanded, the potentiometric method should be used.

Svensk Papperstidning published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, SDS of cas: 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Arbatsky, I. W. published the artcileTitration theory of dilute solutions, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Zeitschrift fuer Analytische Chemie (1938), 117-26, database is CAplus.

The theory of titrating dilute solutions is discussed with respect to the magnitude of the error and the determination of the proper correction values. The titration of carbonates with phenolphthalein and α-naphtholphthalein as indicators is discussed in detail and the formulas for determining the correction factor are worked out. The advantages of the latter indicator are pointed out with respect to this titration.

Zeitschrift fuer Analytische Chemie published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Hosoi, Kazuo published the artcileCompetition between P1 [inorganic orthophosphate] and pH indictors in photosynthetic ATP formation in chromatophores of Rhodospirillum rubrum, Application In Synthesis of 596-01-0, the publication is Journal of Biochemistry (1973), 74(6), 1275-8, database is CAplus and MEDLINE.

The effects of 8 different pH indicators on the activities for ATP formation in the light and for ATP-Pi exchange in the dark in chromatophores from a carotenoidless mutant (G-9) of R. rubrum were studied. The ratio of the amount of dye bound to chromatophores to the total amount of dye added to the mixture were constant at appropriate concentrations Neither added ATP nor illumination influenced the amount of dye bound with chromatophores. Concentrations of 0.1mM α-naphtholphthalein and Bromcresol Green inhibited the activity for ATP formation and the ATP-Pi exchange but the bindings with chromatophores were ∼78% and 18%, resp., indicating that the binding of pH indicators was not essential for the inhibitions.

Journal of Biochemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kato, Harutoshi published the artcilePrecise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure-activity relationship methods, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Drug Metabolism and Pharmacokinetics (2017), 32(3), 179-188, database is CAplus and MEDLINE.

The constitutive androstane receptor (CAR, NR1I3) regulates the expression of numerous drug-metabolizing enzymes and transporters. The upregulation of various enzymes, including CYP2B6, by CAR activators is a critical problem leading to clin. severe drug-drug interactions (DDIs). To date, however, few effective computational approaches for identifying CAR activators exist. In this study, we aimed to develop three-dimensional quant. structure-activity relationship (3D-QSAR) models to predict the CAR activating potency of compounds emerging in the drug-discovery process. Models were constructed using comparative mol. field anal. (CoMFA) based on the mol. alignments of ligands binding to CAR, which were obtained from ensemble ligand-docking using 28 compounds as a training set. The CoMFA model, modified by adding a lipophilic parameter with calculated logD_7.4 (S+logD_7.4), demonstrated statistically good predictive ability (r² = 0.99, q² = 0.74). We also confirmed the excellent predictability of the 3D-QSAR model for CAR activation (r²_pred = 0.71) using seven compounds as a test set for external validation. Collectively, our results indicate that the 3D-QSAR model developed in this study provides precise prediction of CAR activating potency and, thus, should be useful for selecting drug candidates with minimized DDI risk related to enzyme-induction in the early drug-discovery stage.

Drug Metabolism and Pharmacokinetics published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Matsuo, Shigeru published the artcileSynthesis and characterization of new fluorescent poly(arylene ether)s, Application of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (1994), 32(6), 1071-6, database is CAplus.

The poly(arylene ether)s were prepared by the nucleophilic aromatic substitution polymerization of phenolphthalin and its derivatives with activated aromatic difluorides. The polymers had glass transition temperatures of 210-240°. Though the monomers have no fluorescence, the resulting polymers fluoresced with a light green color in solid and solution states. The maximum excitation and emission wavelengths are 420 nm and 247 nm, resp. In the polymer solutions, the fluorescence intensity decreased gradually, but the intensity was recovered by heating the polymer at 220° for a few minutes. The fluorescent polymer had a stable radical. A model compound having the same repeating unit as the polymer was also prepared The fluorescence properties of this model were almost the same as those of the polymers.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem