Yoshida, N.’s team published research in Organohalogen Compounds in 2007 | CAS: 52010-22-7

Organohalogen Compounds published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Formula: C8H5ClO2.

Yoshida, N. published the artcileReductive dechlorination of PCBs and other chlorinated compounds by novel anaerobic bacterial species, Formula: C8H5ClO2, the main research area is anaerobic bacteria polychlorinated biphenyl chlorinated compound reductive dechlorination.

Bacteria that can reductively dechlorinate chlorinated compounds such as polychlorinated biphenyls (PCBs) and polychlorinated dibenzo-p-dioxins (PCDDs) have been receiving much attention in the field of environmental science and technol. In this study, the enrichment of bacteria that dechlorinate PCBs and PCDDs was performed by the sequentially transferred culture amended with 4,5,6,7-tetrachlorophthalide (fthalide) and single fatty acids from an uncontaminated paddy field. The enrichment cultures amended with lactate (KFL) or formate (KFF) maintained the activity to dechlorinate fthalide to 4-chlorophthalide in the sequential transfer but not the culture amended with acetate and butyrate. The only KFL-culture dechlorinated diverse chlorinated compounds including 2,3,4,5-tetrachlorobiphenyl, 2,3,4-trichlorobiphenyl, 1,2,3-trichlorodibenzo-p-dioxin. A further enrichment of KLF-culture provided an enrichment culture, KFC4A-culture, containing uniformly small short rods. Microbial community anal. based on 16S rRNA genes revealed the involvement of two phylogenetically distinct operational taxonomic units (OTUs) of Dehalobacter sp. (FTH1 and FTH2) with the dechlorination of chlorinated compounds Dehalobacter restrictus TEA was their closest relative, and had 97.5% and 97.3% of 16SrRNA gene similarities for FTH1 and FTH2, resp. These results demonstrate the capacity of uncontaminated paddy soil to dechlorinate PCBs and PCDDs, and the involvement of Dehalobacter sp.

Organohalogen Compounds published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Formula: C8H5ClO2.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Yoshida, Naoko’s team published research in Applied and Environmental Microbiology in 2009-04-28 | CAS: 52010-22-7

Applied and Environmental Microbiology published new progress about Dechlorination. 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Category: benzofurans.

Yoshida, Naoko published the artcileA novel Dehalobacter species is involved in extensive 4,5,6,7-tetrachlorophthalide dechlorination, Category: benzofurans, the main research area is novel Dehalobacter tetrachlorophthalide dechlorination waste fungicide rice blast Dehalobacter.

The purpose of this study was the enrichment and phylogenetic identification of bacteria that dechlorinate 4,5,6,7-tetrachlorophthalide (com. designated “”fthalide””), an effective fungicide for rice blast disease. Sequential transfer culture of a paddy soil with lactate and fthalide produced a soil-free enrichment culture (designated the “”KFL culture””) that dechlorinated fthalide by using hydrogen, which is produced from lactate. Phylogenetic anal. based on 16S rRNA genes revealed the dominance of two novel phylotypes of the genus Dehalobacter (FTH1 and FTH2) in the KFL culture. FTH1 and FTH2 disappeared during culture transfer in medium without fthalide and increased in abundance with the dechlorination of fthalide, indicating their growth dependence on the dechlorination of fthalide. Dehalobacter restrictus TEA is their closest relative, with 97.5% and 97.3% 16S rRNA gene similarities to FTH1 and FTH2, resp.

Applied and Environmental Microbiology published new progress about Dechlorination. 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Category: benzofurans.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

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Biodegradable plastics (BPs) were evaluated for their applicability as sustainable and solid H2 donors for microbial reductive dechlorination of 4,5,6,7-tetrachlorophthalide (fthalide). After a screening test of several BPs, the starch-based plastic (SP) that produced the highest levels of H2 was selected for its use as the sole H2 donor in this reaction. Fthalide dechlorination was successfully accomplished by combining an H2-producing SP culture and a KFL culture containing Dehalobacter species, supplemented with 0.13% and 0.5% SP, respectively. The efficiency of H2 use in dechlorination was evaluated in a combined culture containing the KFL culture and strain Clostridium sp. Ma13, a new isolate that produces H2 from SP. Results obtained with this culture indicated increased H2-fraction for fthalide dechlorination much more in this culture than in compared with a KFL culture supplemented with 20mM lactate, which are 0.75 H2·glucose-1 and 0.015 H2·lactate-1 in mol ratio, respectively.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2596O – PubChem

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A series of n-butylphthalide derivatives were designed and synthesized. The in vitro activities of these compounds were evaluated by a resting tension of isolated rat thoracic aorta ring assay. Compounds 4g and 4i were found to be more active than n-butylphthalide.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2595O – PubChem

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Derivatives of 1,3-dihydro-3-(2-hydroxyethyl) -2H-isoindol-1-one are disclosed. The derivatives are useful for treating ulcers in a mammal and for preventing or decreasing the secretion or availability of excessive amounts of gastric or hydrochloric acid in a mammal suffering from hyperchlorhydria and/or associated conditions.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2587O – PubChem

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An efficient method for preparation of substituted 1,2-phenylenedimethanols and aliphatic 1,4-diols that are valuable intermediates in organic synthesis, has been developed by the base-promoted reduction of isobenzofuran-1(3H)-ones and gamma-lactones with silane under mild conditions. Compared with traditional procedures using stoichiometric amounts of metal hydrides and alkyl reductants, the present method avoids the use of sensitive reagents and is operationally simple and a broad variety of functional groups are tolerated.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2592O – PubChem

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Disclosed is a method for removing impurities from products derived from oxidation of an ortho-dialkylaromatic compound which comprises at least one step selected from the group consisting of extraction of an aqueous solution comprising aromatic dicarboxylic acid product with an organic solvent and extraction of an organic solution comprising aromatic anhydride product with an aqueous bicarbonate solution for a time period insufficient to allow hydrolysis of anhydride to acid.

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Benzofuran – Wikipedia,
Benzofuran | C8H2588O – PubChem

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17O chemical shift data (natural abundance) for 3-substituted phthalic anhydrides and 4- and 7-substituted phthalides in acetonitrile at 75 deg C are reported.Steric interactions of substituents ortho to the carbonyl groups result in deshielding effects (9-22 ppm) relative to parent compounds regardless of the electronic character of the substituents.Factors contributing to the deshielding effects are discussed.The relationship between 17O chemical shifts and regiochemistry of the phthalic anhydrides is discussed.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2590O – PubChem

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A compound of the formula (I): wherein: A and B together represent an optionally substituted, fused aromatic ring; X and Y are selected from CH and CH, CF and CH, CH and CF and N and CH respectively; RC is selected from H, C1-4 alkyl; and R1 is selected from C1-7 alkyl, C3-20 heterocyclyl and C5-20 aryl, which groups are optionally substituted; or RC and R1 together with the carbon and oxygen atoms to which they are attached form a spiro-C5-7 oxygen-containing heterocyclic group, which is optionally substituted or fused to a C5-7 aromatic ring.

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Benzofuran – Wikipedia,
Benzofuran | C8H2586O – PubChem

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A problem of 3-methoxyphthalide reduction by metal hydrides was reinvestigated. Various effects controlling selectivity of reductions in 3-substituted phthalides were studied, and a qualitative interpretation of the results is now proposed. Methods for obtaining enhanced yields of one or the other lactonic product were developed.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2594O – PubChem