A new application about 87-41-2

Synthetic Route of 87-41-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 87-41-2.

Synthetic Route of 87-41-2, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 87-41-2, Name is Isobenzofuran-1(3H)-one, SMILES is O=C1OCC2=C1C=CC=C2, belongs to benzofurans compound. In a article, author is Ye, Yan-Song, introduce new discover of the category.

Novel Meroterpenoids from Hypericum patulum: Highly Potent Late Na(v)1.5 Sodium Current Inhibitors

Hypulatones A and B (1 and 2), two racemic meroterpenoids possessing an unprecedented spiro[benzofuran-2,1′-cycloundecan]-4′-ene-4,6(5H)-dione core, were characterized from Hypericum patulum. Compound 2 was found to significantly inhibit the late current of Na(v)1.5 (late I-Na, IC50 = 0.2 mu M). Importantly, 2 exhibited remarkable separation (>100-fold) of late I-Na relative to peak I-Na and notable selectivity over Ca(v)3.1, K(v)1.5, and hERG. 1 showed comparable inhibition on late I-Na compared to that of 2 with poorer selectivity.

Synthetic Route of 87-41-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 87-41-2.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem