The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide(SMILESS: O=C(N(C1=CC=CC=C1)N2C3=CC=CC=C3)[C-](CCCC)C2=O.[Na+],cas:129-18-0) is researched.Safety of 1-(Bromomethyl)-4-ethylbenzene. The article 《Nonsteroidal antiinflammatory agents and the histamine-releasing agent 48/80》 in relation to this compound, is published in Annales Pharmaceutiques Francaises. Let’s take a look at the latest research on this compound (cas:129-18-0).
Orally administered metiazinic acid [13993-65-2], niflumic acid [4394-00-7], ibuprofen [15687-27-1], indomethacin [53-86-1], and phenylbutazone [50-33-9] had no effect against the ability of compound 48/80 to release histamine [51-45-6] from mast cells, to increase skin capillary permeability, or to cause rat paw edema. When administered locally, the antiinflammatory agents inhibited 48/80 activity at concentrations which could not be attained following oral administration.
There are many compounds similar to this compound(129-18-0)Reference of Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem