With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.610-93-5,6-Nitroisobenzofuran-1(3H)-one,as a common compound, the synthetic route is as follows.
610-93-5, 6-Nitrophthalide (20 mmol) was dissolved in ethyl acetate (200 mL) and methanol (50 mL) and hydrogenated at atmospheric pressure in the presence of 10% Pd/C (0.3 g). After 18 h the reaction mmixture was filtered through a bed of celite and the filtrate was removed under reduced pressure. The residue was washed with cold ethyl acetate (20 mL) to yield 6-aminophthalide.5
The synthetic route of 610-93-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Strydom, Belinda; Bergh, Jacobus J.; Petzer, Jacobus P.; Bioorganic and Medicinal Chemistry Letters; vol. 23; 5; (2013); p. 1269 – 1273;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem