Electric Literature of C9H7BrO3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Methyl 4-bromo-2-formylbenzoate, is researched, Molecular C9H7BrO3, CAS is 1260795-42-3, about Catalytic cascade aldol-cyclization of tertiary ketone enolates for enantioselective synthesis of keto-esters with a C-F quaternary stereogenic center. Author is Sha, Wanxing; Zhang, Lijun; Zhang, Wenzhong; Mei, Haibo; Soloshonok, Vadim A.; Han, Jianlin; Pan, Yi.
The first asym. catalytic aldol-cyclization reaction of detrifluoroacetylatively in situ generated enolates with Me 2-formylbenzoate was reported. This reaction tolerates a wide range of substrates, affording fluorinated quaternary stereogenic α,α-dialkyl/cyclo-alkyl-β-ketoesters, e.g., I, with good yields, high diastereo-(94% de) and enantioselectivity (96% ee) at room temperature
Different reactions of this compound(Methyl 4-bromo-2-formylbenzoate)Electric Literature of C9H7BrO3 require different conditions, so the reaction conditions are very important.