64169-34-2, 5-Bromoisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step A: 5-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)-2-benzofuran-l(3H)-one To a microwave tube containing a stir bar was added 5-bromo-2-benzofuran-l (3H)-one (0.10 g, 0.47 mmol), Bis(pinacolato)diboron (0.12 g, 0.47 mmol), bis(diphenylphosphino)palladium(II) (0.010 g, 0.014 mmol), potassium acetate (0.14 g, 1.4 mmol) and anhydrous toluene (10 mL). The resulting mixture was capped and heated at 80 C for 2 h. The reaction mixture was diluted with benzene and washed successively with water and brine. The organic layer was then dried (Na2S04), filtered, and concentrated. The resulting residue was purified by silica gel column chromatography (hexanes/EtOAc = 1/1) to provide 5- (4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)-2-benzofuran-l(3H)-one. LC/MS: [(M+l)]+ =261.
64169-34-2, The synthetic route of 64169-34-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; WALSH, Shawn; PASTERNAK, Alexander; CATO, Brian; FINKE, Paul, E.; FRIE, Jessica; FU, Qinghong; KIM, Dooseop; PIO, Barbara; SHAHRIPOUR, Aurash; SHI, Zhi-Cai; TANG, Haifeng; WO2013/39802; (2013); A1;,
Benzofuran – Wikipedia
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