10242-12-3, 5-Nitrobenzofuran-2-carboxylic acid is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,10242-12-3
Compound 69 (2.0 g, 9.66 mmol) and beta-alanine methylester¡¤HCl (1.752 g, 12.55 mmol) weredissolved in dimethylformamide (48.3 mL). 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(2.41 g, 12.55 mmol) and 4-dimethylaminopyridine (0.59 g, 4.83 mmol) were added and thereaction was stirred under Ar at room temperature for 2 d. An additional amount of beta-alaninemethylester¡¤HCl (337 mg), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (462 mg), and 4-dimethylaminopyridine (147 mg) were added and stirred for an additional night. The reaction wascooled in an ice bath and then water was added to precipitate the desired compound. The solutionwas filtered to obtain compound 70 (2.82 g, 100% yield), which used without further purification.
As the paragraph descriping shows that 10242-12-3 is playing an increasingly important role.
Reference£º
Article; Reid, Emily E.; Archer, Katie E.; Shizuka, Manami; McShea, Molly A.; Maloney, Erin K.; Ab, Olga; Lanieri, Leanne; Wilhelm, Alan; Ponte, Jose F.; Yoder, Nicholas C.; Chari, Ravi V.J.; Miller, Michael L.; Bioorganic and Medicinal Chemistry Letters; vol. 29; 17; (2019); p. 2455 – 2458;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem