133720-60-2, 7-Bromobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A stirred solution of diisopropylamine (0.65 mL, 4.7 mmol) in THF (15 L) was cooled to 5C and n-BuLi (2.5 M in hexanes, 1.9 mL, 4.7 mmol) was added dropwise over 5 min. The mixture was stirred at 5C for 15 min and cooled to – 700C. Chlorotrimethylsilane (0.59 mL, 4.7 mmol) was added followed by a solution of 7-bromobenzofuran (0.46 g, 2.35 mmoi) in THF (5 mL). The mixture was stirred at -700C for 1.5 h and poured into sat’d aq NH4Cl (80 mL). The mixture was diluted with 5% aq HCI (20 mL) and extracted with ether (2 x 80 mL). The combined ether extracts were washed with sat’d aq NaHCO3 (50 mL), dried over MgSO4 and concentrated to leave crude 7-bromo-2-(trimethylsilyl)benzofuran (0.62 g, 98%) as a yellow oil.
133720-60-2, As the paragraph descriping shows that 133720-60-2 is playing an increasingly important role.
Reference£º
Patent; VITAE PHARMACEUTICALS, INC.; WO2007/117560; (2007); A2;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem