With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15832-09-4,6-Methoxy-3(2H)-benzofuranone,as a common compound, the synthetic route is as follows.
General procedure: Classical heating procedure A: 1g of Al2O3-KF was added to the benzofuranone derivative (0.6 mmol) and the aldehyde (1.0-1.5 eq) dissolved in acetonitrile (1-2 mL). The mixture was evaporated under vacuum and the resulting solid was heated at 70 C until TLC showed disappearance of the starting material (3-8 h). The mixture was extracted with ethanol and Al2O3-KF was removed by filtration. The filtrate was evaporated under reduced pressure to afford the corresponding crude aurone., 15832-09-4
As the paragraph descriping shows that 15832-09-4 is playing an increasingly important role.
Reference£º
Article; Boussafi, Karima; Villemin, Didier; Bar, Nathalie; Belghosi, Mabrouk; Journal of Chemical Research; vol. 40; 9; (2016); p. 567 – 569;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem