SeO2-Mediated One-Pot Synthesis of 3-Cyanofurans from 3-Oxo-3-arylpropanenitriles and Substituted Acetaldehydes was written by Zhou, Jie;Zhu, Xinhai;Huang, Manna;Wan, Yiqian. And the article was included in European Journal of Organic Chemistry in 2017.Application In Synthesis of Methyl benzofuran-2-carboxylate This article mentions the following:
An SeO2-mediated one-pot method was established for the synthesis of 3-cyanofurans I (R1 = 2-Cl, 4-OMe, 2-F, 4-Cl, etc.; R2 = i-Pr, t-Bu, Et, etc.) from 3-oxo-3-arylpropanenitriles and substituted acetaldehydes. The generality of the reaction was explored, and a plausible mechanism is proposed. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Application In Synthesis of Methyl benzofuran-2-carboxylate).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Application In Synthesis of Methyl benzofuran-2-carboxylate
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem