Determination of eleven sulfonamides residues in animal foods by high performance liquid chromatography-fluorescence detection after matrix solid phase dispersion extraction was written by Yang, Xiaosong;Yu, Huiju;Qiu, Sha;Sun, Chengjun. And the article was included in Zhongguo Weisheng Jianyan Zazhi in 2013.Application of 38183-12-9 This article mentions the following:
A method for simultaneous determination of eleven sulfonamide residues (SAs), including sulfisomidine, sulfapyridine, sulfadimidin, sulfamoxol, sulfamonomethoxine, sulfamethizol, sulfachloyopyridazine, sulfasoxine, sulfamethoxazole, sulfisoxazole, and sulfabeuzamide, in animal foods by high-performance liquid chromatog. (HPLC) with fluorescence detection using matrix solid-phase dispersion (MSPD) extraction was presented. Animal food sample was crushed and well-distributed with the solid-phase sorbents C18, and then the mixture was loaded in a vacant SPE cartridge, covered with a piece of filter paper on the top of the mixture, rinsed with hexane to remove fat, eluted with 3:1 (volume/volume) Et acetate-dichloromethane solvent to elute the analytes, then the eluant was dried up at 40°C under N2, and finally the residue was re-dissolved with 1.0 mL 1:1 (volume/volume) methanol-0.2% acetic acid, fluorescamine was added to produce fluorescent derivatives The derivatives were determined by HPLC with fluorescence detection, using an Agilent TC-C18 column and a mixture of 0.2% acetic acid solution-acetonitrile as the mobile phase for gradient elution and detected with a fluorescence detector. The linear ranges of eleven sulfonamides were between 0.02 mg/ to 0.40 mg/L with r>0.999. The detection limits were 0.001 mg/L. The min. detectable content was 0.006 mg/kg. The recovery range was between 54% and 105% with relative standard deviations from 1.3% to 6.1%. The method has the advantages of a small amount of organic solvent, short time of anal., high sensitivity, and low detection limit. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Application of 38183-12-9).
4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Application of 38183-12-9
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem