Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Veterinary Pharmacology and Therapeutics called Residue profile of phenylbutazone in the rabbit. A comparative evaluation by tissue kinetics prior to and post-mortem, Author is Toutain, P. L.; Alvinerie, M.; Ruckebusch, Y., which mentions a compound: 129-18-0, SMILESS is O=C(N(C1=CC=CC=C1)N2C3=CC=CC=C3)[C-](CCCC)C2=O.[Na+], Molecular C19H19N2NaO2, COA of Formula: C19H19N2NaO2.
The disposition kinetics and residue levels of Na phenylbutazone (8 mg/kg) were studied in rabbits as a model for cattle. The results suggest that distribution of phenylbutazone can be described by a 2 compartment open model. The elimination half-time is short (2 h), and the estimation of residue levels in muscle, liver, and kidney did not differ significantly before and after bleeding. Apparently, biopsy tissue can be used to determine the tissue phenylbutazone concentration of larger species. Moreover, by using a pharmacokinetic approach based on drug concentrations in plasma, it appeared that the mean resting quantity in the peripheral compartment was very close to the exptl. data for the muscle.
The article 《Residue profile of phenylbutazone in the rabbit. A comparative evaluation by tissue kinetics prior to and post-mortem》 also mentions many details about this compound(129-18-0)COA of Formula: C19H19N2NaO2, you can pay attention to it, because details determine success or failure
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem