On October 31, 2018, Wang, Xuan; Ma, Guobin; Peng, Yu; Pitsch, Chloe E.; Moll, Brenda J.; Ly, Thu D.; Wang, Xiaotai; Gong, Hegui published an article.Product Details of 60770-67-4 The title of the article was Ni-Catalyzed Reductive Coupling of Electron-Rich Aryl Iodides with Tertiary Alkyl Halides. And the article contained the following:
This work illustrates the reductive coupling of electron-rich aryl halides with tertiary alkyl halides under Ni-catalyzed cross-electrophile coupling conditions, which offers an efficient protocol for the construction of all carbon quaternary stereogenic centers. The mild and easy-to-operate reaction tolerates a wide range of functional groups. The utility of this method is manifested by the preparation of cyclotryptamine derivatives, wherein successful incorporation of 7-indolyl moieties is of particular interest as numerous naturally occurring products are composed of these key scaffolds. DFT calculations have been carried out to investigate the proposed radical chain and double oxidative addition pathways, which provide useful mechanistic insights into the part of the reaction that takes place in solution The experimental process involved the reaction of 5-Iodobenzofuran(cas: 60770-67-4).Product Details of 60770-67-4
The Article related to all carbon quaternary stereogenic center synthesis, reductive coupling electron rich haloarene tertiary alkyl halide mechanism, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Product Details of 60770-67-4
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem