652-12-0, Name is Tetrafluorophthalic anhydride, belongs to benzofurans compound, is a common compound. Recommanded Product: 652-12-0In an article, once mentioned the new application about 652-12-0.
The synthesis and tumor necrosis factor (TNF)-alpha production enhancing activity of substituted 3′-methyl-thalidomides on human leukemia cell line HL-60 stimulated with 12-O-tetradecanoyl-phorbol 13-acetate (TPA) are described. Though the introduction of an electron-donating amino group at the phthaloyl moiety of alpha-methylthalidomides enhanced the activity, substituted alpha-methylthalidomides showed decreased stereoselectivity as compared to that of non-substituted alpha-methylthalidomide. The data indicates that the TNF-alpha production enhancing activity of thalidomide derivatives depends on both the electronic-state of substituents at the fused benzene ring and the stereochemistry of the glutarimide moiety.
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3743O – PubChem