The Absolute Best Science Experiment for 70539-42-3

Here is just a brief introduction to this compound(70539-42-3)Electric Literature of C18H20N2O12, more information about the compound(Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate) is in the article, you can click the link below.

Bhattacharya, Ushashi; Jhou, Jia-Fong; Zou, Yi-Fong; Abrigo, Gerald; Lin, Shu-Wei; Chen, Yun-Hsuan; Chien, Fan-Ching; Tai, Hwan-Ching published an article about the compound: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate( cas:70539-42-3,SMILESS:O=C(ON1C(CCC1=O)=O)CCC(OCCOC(CCC(ON2C(CCC2=O)=O)=O)=O)=O ).Electric Literature of C18H20N2O12. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:70539-42-3) through the article.

Synaptosomes are subcellular fractions prepared from brain tissues that are enriched in synaptic terminals, widely used for the study of neural transmission and synaptic dysfunction. Immunofluorescence imaging is increasingly applied to synaptosomes to investigate protein localization. However, conventional methods for imaging synaptosomes over glass coverslips suffer from formaldehyde-induced aggregation. Here, we developed a facile strategy to capture and image synaptosomes without aggregation artifacts. First, ethylene glycol bis(succinimidyl succinate) (EGS) is chosen as the chem. fixative to replace formaldehyde. EGS/glycine treatment makes the zeta potential of synaptosomes more neg. Second, we modified glass coverslips with 3-aminopropyltriethoxysilane (APTES) to impart pos. charges. EGS-fixed synaptosomes spontaneously attach to modified glasses via electrostatic attraction while maintaining good dispersion. Individual synaptic terminals are imaged by conventional fluorescence microscopy or by super-resolution techniques such as direct stochastic optical reconstruction microscopy (dSTORM). We examined tau protein by two-color and three-color dSTORM to understand its spatial distribution within mouse cortical synapses, observing tau colocalization with synaptic vesicles as well postsynaptic densities.

Here is just a brief introduction to this compound(70539-42-3)Electric Literature of C18H20N2O12, more information about the compound(Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate) is in the article, you can click the link below.

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem