The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate, is researched, Molecular C6H11ClO3, CAS is 90866-33-4, about Mathematical modeling of asymmetric reduction of ethyl 4-chloro acetoacetate by bakers’ yeast, the main research direction is chloro acetoacetate stereoselective enzymic reduction Saccharomyces; stereoselective reduction reaction kinetics modeling.Application of 90866-33-4.
A mathematic model was developed to simulate the asym. reduction of Et 4-chloro acetoacetate (ECA) by bakers’ yeast. The model of the process considered the kinetics of enzymic reaction, the effect of substrate inhibition and the spontaneous degradation of the substrate. The reaction kinetics of the ECA degradation was determined empirically. The inhibition by the substrate was analyzed and the apparent kinetic constants of the overall enzymic reaction, of the S-enzymes and of the R-enzymes, were estimated individually. The system of equations was solved numerically using the Runge-Kutta method. The close correlation between the predicted and exptl. results concerning product formation, reaction yield and optical purity of product under various substrate concentrations, implied the reliability of the established model.
Different reactions of this compound((R)-Ethyl 4-chloro-3-hydroxybutanoate)Application of 90866-33-4 require different conditions, so the reaction conditions are very important.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem