652-39-1, 4-Fluoroisobenzofuran-1,3-dione is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
652-39-1, General procedure: To a solution of compounds 2a-2h (5 mmol) in acetic anhydride (5 mL) and triethylamine (2.5 mL) was added ethyl acetoacetate (0.71 mL, 5.5 mmol) under argon. The reaction mixture was stirred at rt for 12 h and then poured into the mixture of concentrated HCl (6 g) and ice-water (6 g). After that, the reaction mixture was stirred at rt for 30 min, additional HCl (8.8 mL, 5M) was added into the mixture, and then the reaction mixture was refluxed for 2 h. After the crude product was cooled to rt, water (100 mL) was added and the reaction mixture was extracted with DCM (2 100 mL). The combined organic layers were washed with brine and then dried (Na2SO4). After removing the solvent, the residue was purified by flash column chromatography.
As the paragraph descriping shows that 652-39-1 is playing an increasingly important role.
Reference£º
Article; Guo, Shenquan; Zhang, Niuniu; Tang, Xiangzheng; Mao, Zhifeng; Zhang, Xuejing; Yan, Ming; Xuan, Yining; Chinese Chemical Letters; vol. 30; 2; (2019); p. 406 – 408;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem