18761-31-4, 5-Nitrobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Further purification by column chromatography on silica gel (eluted with ethyl acetate/heptane 3:1) yielded 3.2 g of pure 5-nitro-3-(1-piperidylcarbonyl)-2,3-dihydrobenzofuran which crystallized upon standing. Mp: 108-114 C. 5-Amino-3-(1-piperidylcarbonyl)-2,3-dihydrobenzofuran: To a solution of all of the 5-nitrobenzofuran in 90% ethanol (50 ml) kept at reflux were added small portions of Fe powder (in total 2.5 g) and concentrated HCl (in total 0.1 ml) during 10 min. The mixture was refluxed for another hour. The inorganic precipitates were filtered off and the mixture was poured onto brine and ethyl acetate (250 ml). work-up of the organic phase afforded 1 g of crystalline 5-aminobenzofuran derivative., 18761-31-4
As the paragraph descriping shows that 18761-31-4 is playing an increasingly important role.
Reference£º
Patent; H. Lundbeck A/S; US5807889; (1998); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem