19477-73-7, 6-Bromoisobenzofuran-1(3H)-one is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
6-Bromo-3H-isobenzofuran-1-one (5.0 g, 23.47 mmol) was weighed and added to a three-neck bottle.Measure tetrahydrofuran: methanol: water (2:1:1, 80 mL), add to a three-neck bottle, stir for 10 minutes.After dissolution, lithium hydroxide (3.45 g, 70.42 mmol) was added and stirred at room temperature for 16 hours.After the reaction of the raw materials was monitored by thin layer chromatography, the reaction mixture was concentrated, and water (100 mL) was added.The pH was adjusted to 3 with 2N hydrochloric acid and extracted three times with 100 mL of ethyl acetate.The organic phase is then washed with water and the organic phase is washed with saturated sodium chloride.Dried over anhydrous sodium sulfate, filtered and concentrated.This gave 3.3 g (91%) of a white solid.
19477-73-7, The synthetic route of 19477-73-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Shanghai Yilishe Biological Co., Ltd.; Zhang Lihai; Gao Zhichao; Huang Ximing; Liu Hui; Hu Min; Jiang Yan; (72 pag.)CN108250058; (2018); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem