Downstream synthetic route of 641-70-3

The synthetic route of 641-70-3 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.641-70-3,3-Nitrophthalic anhydride,as a common compound, the synthetic route is as follows.,641-70-3

To 580 ml of ammonia (cone, aqueous solution) 400 g (2.07 mol) of 2 were added. The temperature rose to 600C and the mixture was stirred for 1 h. After addition of 200 ml of ethanol the mixture was cooled to 5C. The resulting solid was isolated, washed with MTBE and dried in a vacuum oven at 400C. Yield: 81.6%.

The synthetic route of 641-70-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ABBOTT GMBH & CO. KG; WO2007/6566; (2007); A1;,
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