Synthesis and biological activities of pyrazolinobenzofuro[3,2-d]pyridimidines was written by Basawaraj, Raga;Goled, S. N.;Khandre, Omakar;Sangapure, S. S.. And the article was included in Indian Journal of Heterocyclic Chemistry in 2011.Name: 3-Aminobenzofuran-2-carboxamide This article mentions the following:
2-(2,4,6-Trimethoxyphenyl/α-naphthyl)-4-hydrazinobenzofuro[3,2-d]pyrimidines 5,6 were prepared by nucleophilic substitution of 2-(trimethoxyphenyl/α-naphthyl)-4-chlorobenzofuro[3,2-d]pyrimidines 3,4 with N2H4.H2O in MeOH. The reaction of 2-substituted 4-hydrazinobenzofuro[3,2-d]pyrimidines 5,6 with Ac2CH2, NCCH2CO2Et, or AcCH2CO2Et in NaOEt furnished pyrazolyl- and pyrazolinylbenzofuro[3,2-d]pyrimidines. These compounds exhibited antimicrobial and anti-inflammatory activity. In the experiment, the researchers used many compounds, for example, 3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7Name: 3-Aminobenzofuran-2-carboxamide).
3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Name: 3-Aminobenzofuran-2-carboxamide
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem