In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Subunit composition of the untransformed glucocorticoid receptor in the cytosol and in the cell, published in 1992-02-15, which mentions a compound: 70539-42-3, Name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, Molecular C18H20N2O12, Category: benzofurans.
Bifunctional reagents were used to exam. the subunit composition of the non-DNA-binding form of the rat and human glucocorticoid receptor. Treatment of intact cells and cell extracts with a reversible cross-linker, followed by electrophoretic anal. of immunoadsorbed receptor revealed that 3 proteins of apparent approx. mol. masses, 90, 53, and 14 kDa are associated with the receptor. The 1st of these was identified immunochem. as a 90-kDa heat-shock protein (hsp90). The complex isolated from HeLa cells contained 2.2 mol hsp90/mol steroid-binding subunit. Crosslinking of the receptor complex in the cytosol completely prevented salt-induced dissociation of the subunits. The cross-linked receptor was electrophoretically resolved into 2 oligomeric complexes of apparent mol. mass 288 kDa and 347 kDa, reflecting the association of the 53-kDa protein with a fraction of the receptor. Since no higher oligomeric complexes could be generated by crosslinking cell extracts under different conditions, it was concluded that most of the untransformed cytosolic receptor is devoid of addnl. components.
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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem