50551-57-0, Name is Ethyl 6-methoxybenzofuran-2-carboxylate, belongs to benzofuran compound, is a common compound. Safety of Ethyl 6-methoxybenzofuran-2-carboxylateIn an article, once mentioned the new application about 50551-57-0.
Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2- phenylethyl)arylamides
A series of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides were prepared, using an efficient three- to five-step synthesis, and evaluated for their inhibitory activity against human cytochrome P450C24A1 (CYP24A1) hydroxylase. Inhibition ranged from IC50 0.3-72 muM compared with the standard ketoconazole IC50 0.52 muM, with the styryl derivative (11c) displaying enhanced activity (IC50 = 0.3 muM) compared with the standard, providing a useful preliminary lead for drug development.
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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3792O – PubChem