Studies in benzofurans: Part I. Synthesis of some benzofuro[3,2-d]pyrimidine derivatives was written by Sangapure, S. S.;Agasimundin, Y. S.. And the article was included in Indian Journal of Chemistry in 1976.Application of 54802-10-7 This article mentions the following:
O-HOC6H4CN was condensed with BrCH2CO2Et, ClCH2CONH2, ClCH2CN, resp., to give o-NC = C6H4OCH2R (R = CO2Et, CONH2, CN), which underwent Thorpe-Ziegler cyclization to give the corresponding benzofuran derivatives I in good yields. I served as intermediates for the synthesis of various benzofuro[3,2-d]pyrimidine derivatives II, III, and IV (R = NH2). III was converted into IV (R = Cl) which on further displacement reactions gives IV (R = MeS, EtS, PhCH2S, MeO, EtO). In the experiment, the researchers used many compounds, for example, 3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7Application of 54802-10-7).
3-Aminobenzofuran-2-carboxamide (cas: 54802-10-7) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Application of 54802-10-7
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem