HPLC of Formula: 70539-42-3. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, is researched, Molecular C18H20N2O12, CAS is 70539-42-3, about Chemical modification and immobilisation of laccase from Trametes hirsuta and from Myceliophthora thermophila. Author is Forde, Jessica; Tully, Elizabeth; Vakurov, Alex; Gibson, Tim D.; Millner, Paul; O’Fagain, Ciaran.
Laccase from two different source organisms, Myceliophthora thermophila and Trametes hirsuta, were subjected to chem. modification in solution by (1) two bifunctional reagents, ethylene-glycol-N-hydroxy succinimide (EGNHS) and glutaraldehyde and (2) by the monofunctional citraconic anhydride. The untreated and chem. modified forms of both enzymes were then immobilized onto three different types of mesoporous silicate (MPS) particle (MCM, CNS and SBA-15). Thermal stabilities of native, modified-soluble and immobilized laccases were then evaluated. Although the two laccases have similar lysine contents, those of M. thermophila are clearly more amenable to chem. modification. Treatment of the M. thermophila enzyme with EGNHS led to a 8.7-fold increase in thermal stability over the free soluble enzyme while glutaraldehyde gave a 5.7-fold increase. Increased activity of M. thermophila laccase occurred only with citraconic anhydride modification (a 3-fold increase), while the glutaraldehyde modification marginally increased the activity of the T. hirsuta enzyme (by 1.2-fold). Upon immobilization onto MPS, the greatest increase in stability was for the glutaraldehyde-treated M. thermophila preparation on SBA-15 (24-fold over the soluble enzyme). Chem. modification of laccase from T. hirsuta with both glutaraldehyde and EGNHS gave only a 2-fold increase in stability, increasing >4-fold upon immobilization onto SBA-15 and MCM-41/98.
In some applications, this compound(70539-42-3)HPLC of Formula: 70539-42-3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem