Pu, Fan published the artcilePalladium (II)-Catalyzed Decarboxylative Cross-Dehydrogenative Coupling: Direct Synthesis of meta-Substituted Biaryls from Aromatic Acids, Recommanded Product: 4-Chlorophthalide, the main research area is aromatic acid palladium catalyst regioselective tandem oxidative coupling decarboxylation; biaryl preparation.
A palladium-catalyzed tandem process of simple aromatic acids was achieved to afford meta-substituted biaryls in moderate to good yields. The reaction proceeded via carboxyl-directed intermol. cross-dehydrogenative coupling and subsequent decarboxylation. The new C-C bonds in this transformation were formed in the ortho position of carboxyl and the reaction tolerates electron-rich acids. Both sym. and unsym. meta-substituted biaryls were directly synthesized via this method.
Advanced Synthesis & Catalysis published new progress about Biaryls Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 52010-22-7 belongs to class benzofurans, name is 4-Chlorophthalide, and the molecular formula is C8H5ClO2, Recommanded Product: 4-Chlorophthalide.
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem