Branched Amine Synthesis via Aziridine or Azetidine Opening with Organotrifluoroborates by Cooperative Bronsted/Lewis Acid Catalysis: An Acid-Dependent Divergent Mechanism was written by Nguyen, Truong N.;May, Jeremy A.. And the article was included in Organic Letters in 2018.Recommanded Product: Potassium benzofuran-2-yltrifluoroborate This article mentions the following:
A practical catalytic method to synthesize β,β- and γ,γ-substituted amines by opening aziridines and azetidines, resp., using alkenyl, alkynyl, or aryl/heteroaryl trifluoroborate salts is described. This reaction features simple open-flask reaction conditions, the use of transition-metal-free catalysis, complete regioselectivity, and high diastereoselectivity. Preliminary mechanistic studies suggest that carbocation formation is disfavored. Stereoretentive addition is favored with Bronsted acid present, while stereoinversion is favored in its absence, indicating divergent mechanisms. In the experiment, the researchers used many compounds, for example, Potassium benzofuran-2-yltrifluoroborate (cas: 929626-27-7Recommanded Product: Potassium benzofuran-2-yltrifluoroborate).
Potassium benzofuran-2-yltrifluoroborate (cas: 929626-27-7) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Recommanded Product: Potassium benzofuran-2-yltrifluoroborate
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem