Preparation and reactions of a benzofurylmercuric compound was written by Izumi, Taeko;Takeda, Toru;Kasahara, Akira. And the article was included in Yamagata Daigaku Kiyo, Kogaku in 1974.Synthetic Route of C10H8O3 This article mentions the following:
2-Benzofurylmercuric chloride (I) was obtained by the reaction of benzofuran (II), 1 equivalent HgCl2, and 2 equivalentsNaOAc. 3H2O in aqueous EtOH at room temperature 5 days; m.p. 274-8°. I was also prepared by the reaction of Na coumarylate with an equivalent amount of HgCl2 in 1 l. water followed by decarboxylation under gentle reflux. Benzofurylation of olefins such as styrene, Et acrylate, Et crotonate, and H2C:CHCN were performed in the presence of Li2PdCl4 in MeOH or MeCN, accompanied by the formation of 2,2′-dibenzofuran (III). Carbonylation of I at 100° 6 hr under 50 atm CO pressure in the presence of Li2PdCl4 in MeOH gave Me coumarylate, 2,2′-dibenzofuryl ketone, and a small amount of III. 2-Acetylation and benzoylation of I with acyl chlorides, coupling reaction to 2,2′-dibenzofurylmercury by Na2S2O3, and 2-bromination with Br were reported. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Synthetic Route of C10H8O3).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Synthetic Route of C10H8O3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem