Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 4412-91-3, Name is 3-Furanmethanol, molecular formula is C5H6O2, belongs to benzofurans compound. In a document, author is Mphahlele, Malose J., introduce the new discover, Recommanded Product: 4412-91-3.
Synthesis, In Vitro Evaluation and Molecular Docking of the 5-Acetyl-2-aryl-6-hydroxybenzo[b]furans against Multiple Targets Linked to Type 2 Diabetes
The 5-acetyl-2-aryl-6-hydroxybenzo[b]furans 2a-h have been evaluated through in vitro enzymatic assay against targets which are linked to type 2 diabetes (T2D), namely, alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B) and beta-secretase. These compounds have also been evaluated for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging method. The most active compounds against alpha-glucosidase and/or PTP1B, namely, 4-fluorophenyl 2c, 4-methoxyphenyl 2g and 3,5-dimethoxyphenyl substituted 2h derivatives were also evaluated for potential anti-inflammatory properties against cyclooxygenase-2 activity. The Lineweaver-Burk and Dixon plots were used to determine the type of inhibition on compounds 2c and 2h against alpha-glucosidase and PTP1B receptors. The interactions were investigated in modelled complexes against alpha-glucosidase and PTP1B via molecular docking.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 4412-91-3. Recommanded Product: 4412-91-3.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem