Extended knowledge of 1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 64169-67-1. In my other articles, you can also check out more blogs about 64169-67-1

Electric Literature of 64169-67-1, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 64169-67-1, Name is 1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile, molecular formula is C15H10FNO. In a Patent,once mentioned of 64169-67-1

The present invention relates to a method for the preparation of citalopram comprising reaction a compound of formula (I) 1with a compound having the formula 2wherein X is a suitable leaving group and R is ?CH2?O?Pg, ?CH2?NPg1Pg2, ?CH?N(CH3)2, ?CH(OR1)(OR2) ?C(OR4)(OR5)(OR6), ?COOR3, ?CH2?CO?NH2, ?CH=CHR7 and ?CONHR8, wherein Pg is a protection group for an alcohol group, Pg1 and Pg2 are protection groups for an amino group, R1 and R2 are independently selected from alkyl, alkenyl, alkynyl and optionally alkyl substituted aryl or aralkyl groups or R1 and R2 together form a chain of 2 to 4 carbon atoms, each of R3, R4, R5, R6 and R7 are independently selected from alkyl, alkenyl, alkynyl and optionally alkyl substituted aryl or aralkyl and R8 is hydrogen or methyl; to form a compound of the formula 3wherein R is as defined above; followed by conversion of the group R to form a dimethylaminomethyl group and isolation of citalopram base or a pharmaceutically acceptable salt thereof.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 64169-67-1. In my other articles, you can also check out more blogs about 64169-67-1

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3882O – PubChem