Erbing, Elis; Sanz-Marco, Amparo; Vazquez-Romero, Ana; Malmberg, Jesper; Johansson, Magnus J.; Gomez-Bengoa, Enrique; Martin-Matute, Belen published an article on February 2 ,2018. The article was titled 《Base- and Additive-Free Ir-Catalyzed ortho-Iodination of Benzoic Acids: Scope and Mechanistic Investigations》, and you may find the article in ACS Catalysis.Application In Synthesis of 7-Iodoisobenzofuran-1(3H)-one The information in the text is summarized as follows:
A protocol for the C-H activation/iodination of benzoic acids catalyzed by a simple iridium complex has been developed. The method described in this paper allows the ortho-selective iodination of a variety of benzoic acids under extraordinarily mild conditions in the absence of any additive or base in 1,1,1,3,3,3-hexafluoroisopropanol as the solvent. The iridium catalyst used tolerates air and moisture, and selectively gives ortho-iodobenzoic acids with high conversions. Mechanistic investigations revealed that an Ir(III)/Ir(V) catalytic cycle operates, and that the unique properties of HFIP enables the C-H iodination using the carboxylic moiety as a directing group. After reading the article, we found that the author used 7-Iodoisobenzofuran-1(3H)-one(cas: 105694-46-0Application In Synthesis of 7-Iodoisobenzofuran-1(3H)-one)
7-Iodoisobenzofuran-1(3H)-one(cas: 105694-46-0) belongs to benzofurans.Application In Synthesis of 7-Iodoisobenzofuran-1(3H)-oneBenzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem