In 2012,RSC Advances included an article by Song, Wen-Jian; Yang, Xiao-Dong; Zeng, Xiang-Hui; Xu, Xiao-Liang; Zhang, Gao-Lan; Zhang, Hong-Bin. HPLC of Formula: 50551-57-0. The article was titled 《Synthesis and cytotoxic activities of novel hybrid compounds of imidazole scaffold-based 2-substituted benzofurans》. The information in the text is summarized as follows:
A series of novel hybrid compounds between 2-substituted benzofuran and imidazole have been prepared and evaluated in vitro against a panel of human tumor cell lines. The results show that the hybrid compounds were more selective towards an ovarian carcinoma cell line (Skov3-3) and suggest that hybrid compounds bearing 2-substituted benzofuran and benzimidazole moieties, as well as imidazolium salts, were vital for modulating cytotoxic activity. Two 2-substituted benzofuran imidazole hybrids may serve as valuable leads for further structural modifications. The title compounds thus formed included 1-[(2-benzofuranyl)methyl]-3-(phenylmethyl)-1H-benzimidazolium bromide (I) and related substances, such as [(benzofuranyl)methyl]imidazole derivatives The synthesis of the target compounds was achieved by a reaction of imidazole derivatives with 2-benzofuranmethanol. In the experimental materials used by the author, we found Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0HPLC of Formula: 50551-57-0)
Ethyl 6-methoxybenzofuran-2-carboxylate(cas: 50551-57-0) belongs to benzofurans.HPLC of Formula: 50551-57-0Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem