58546-89-7, Benzofuran-5-amine is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
58546-89-7, Reference Example 1-14-(Benzofuran-5-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid ethyl ester hydrochloride To a solution of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid ethyl ester (0.383 g, 1.70 mmol) in isopropanol (15 ml) was added 5-aminobenzo[b]furan (0.250 g, 1.88 mmol), and the mixture was heated for 1 hour under reflux.After the completion of the reaction, the reaction mixture was cooled to 0 C., and then the precipitated solid was collected by filtration, washed with diethyl ether, and dried under reduced pressure to give the compound of the Reference Example 1-1 (0.528 g, 1.47 mmol, yield 87%).Mass (EI, m/z): 322 [M]+.1H-NMR (DMSO-d6) delta: 12.95 (1H, br s), 11.06 (1H, s), 8.39 (1H, s), 8.24 (1H, d, J=1.7 Hz), 8.15 (1H, s), 8.02 (1H, d, J=2.0 Hz), 7.65 (1H, d, J=8.8 Hz), 7.56 (1H, dd, J=8.8, 2.0 Hz), 7.02 (1H, d, J=1.7 Hz), 4.40 (2H, q, J=7.1 Hz), 1.37 (3H, t, J=7.1 Hz).
58546-89-7 Benzofuran-5-amine 1477152, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Patent; UBE INDUSTRIES, LTD.; US2012/149902; (2012); A1;,
Benzofuran – Wikipedia
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