On August 13, 2019, Chen, Qingcai; Zhao, Jun; Zhao, Xiaowei; Chen, Xiangfeng; Zong, Zaiwei; Lu, Hui published a patent.Application of 60770-67-4 The title of the patent was Nitrogen-containing heterocyclic compound, preparation method and application. And the patent contained the following:
The invention disclosed a kind of nitrogen-containing heterocyclic compound,its preparation method and application as potassium ion competitive acid retardant or gastric acid secretion inhibitor. The claimed compound is shown in structure I (ring A = saturated or unsaturated five member ring; X1,X2,X3 = C, N, O, S, etc.; a,b = bridge atom C or N; R1 = -SO2R4, -(CH2)nR4, or -CHR4R5; R4 = aryl, arylalkyl, arylalkenyl, benzocyclo, etc.; R5 = halo, nitro, cyano, etc.; n = 0, 1-6 integers; R2 = aryl, arylalkyl, heteroaryl, etc.; R3 = H, alkyl cycloalkyl). The claimed compound is prepared via multiple steps (example procedure given). The prepared compound has proton pump H+/K+-ATP enzyme inhibition effect, and is used for preventing and treating diseases related to inhibition of gastric acid secretion, such as peptic ulcer, zollinger-ellison syndrome, gastritis, erosive esophagitis, reflux esophagitis, symptomatic gastroesophageal reflux disease and the like. The experimental process involved the reaction of 5-Iodobenzofuran(cas: 60770-67-4).Application of 60770-67-4
The Article related to nitrogen containing heterocycle preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Application of 60770-67-4
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem