The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 97148-39-5, Name is Ammonium (Z)-2-(furan-2-yl)-2-(methoxyimino)acetate, SMILES is O=C([O-])/C(C1=CC=CO1)=NOC.[NH4+], in an article , author is Tang, Wendi, once mentioned of 97148-39-5, Computed Properties of C7H10N2O4.
Small molecules targeting HIF-1 alpha pathway for cancer therapy in recent years
Hypoxia is a very important feature of tumors, especially for solid tumors, and it was demonstrated highly relevant with aggressive biology, including anti-apoptosis, vasculogenesis and radiation or chemotherapy resistance. Correlatively, hypoxia-inducible factors 1-alpha (HIF-1 alpha), which the wildest contribution of hypoxia-inducible factors (HIFs), plays a crucial role in the adaptation of tumor cells to hypoxia via upregulating the transcription of the oncogene and downregulating the transcription of suppressor gene. This review focus on the HIF-1 alpha regulation including hydroxylation and acetylation, growth factors pathway, heat shock proteins(HSPs), and small molecule inhibitors for HIF-1 alpha directly or indirectly.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem