One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 10242-12-3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 10242-12-3, Name is 5-Nitrobenzofuran-2-carboxylic acid, molecular formula is C9H5NO5
The development of a clear chemical process to produce diverse value-added chemicals from low-cost raw materials is a particularly attractive concept and represents a considerable challenge in sustainable organic synthesis. Herein, two highly efficient and clear methods for the synthesis of quinolone derivatives based on a linear/branched domino protocol under sustainable conditions were established. The main advantages of these protocols are the simple experimental procedure, high bond-forming efficiency, inexpensive readily available starting materials, moderate to excellent yields with good functional group compatibility, and nonchromatographic purification, which render these methods particularly attractive for the sustainable preparation of biologically and medicinally interesting molecules. To demonstrate the practical utility of our protocol, existing pharmaceutical sarafloxacin was successfully synthesized. Furthermore, a postulated reaction pathway including condensation reaction/nucleophilic aromatic substitution/Friedel-Crafts reaction for these domino reactions is also discussed.
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3519O – PubChem