Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of 5-Bromobenzofuran-3(2H)-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 54450-20-3
An organocatalytic asymmetric formal aza-[3+3]cycloaddition of readily available N-Tosyl-3-aminobenzofuran with alpha,beta-unsaturated aldehydes was developed for the first time. This method enables the facile synthesis of biologically active and synthetically challenging polysubstituted fused benzofuran derivatives bearing two stereocenters in high yields with excellent diastereo-, and enantioselectivity (up to >20 : 1 dr, and >99% ee). (Figure presented.).
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3605O – PubChem