Related Products of 125-20-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.125-20-2, Name is Thymolphthalein, molecular formula is C28H30O4. In a Article，once mentioned of 125-20-2
Objective: Bisphosphonates (BPs) have been widely used in the treatment of bone disorders due to their ability to modulate bone turnover. The biological mechanisms through BFs exert their effects on osteoclasts are well established. However, the role of BFs on the osteoblasts is controversial. The present study aimed to evaluate the effects of risedronate on osteoblastic cells. Design: MC3TE-E1 cells were exposed to risedronate at 0, 10-8, 10-6, 10-4, and 10-3 M. The following parameters were assayed: (1) cell proliferation by hemocytometer counting after 24, 48 and 72 h, (2) cell viability by MTT assay after 24, 48 and 72 h, (3) Type I Collagen quantification by ELISA after 24, 48 and 72 h, (3) alkaline phosphatase activity after 7 and 10 days and (4) matrix mineralization after 14 days. Results: After 24 h, risedronate did not affect both cell proliferation and viability (p > 0.05). However, after 48 and 72 h, a decrease in cell proliferation and viability was detected in osteoblastic cultures exposed to risedronate at 10-4 and 10-3 M (p < 0.05). After 48 and 72 h, Type I Collagen synthesis was stimulated by risedronate at 10-4 M (p < 0.05). High levels of ALP activity were detected in cultures exposed to risedronate at 10-4 M after 7 and 10 days (p < 0.05). After 14 day, high calcium content was observed in cultures exposed to risedronate at 10-4 M (p > 0.05). Conclusion: These results indicated that risedronate can promote osteoblast differentiation.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 125-20-2, and how the biochemistry of the body works.Related Products of 125-20-2
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H4344O – PubChem