Archives for Chemistry Experiments of 5-Nitrobenzofuran-2-carboxylic acid

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A series of substituted 1,3,4-oxadiazole, 1,2,4-triazole, and 1,3,4-thiadiazole derivatives of the substituted 3-carboethoxy-1,4-dihydro-4- oxoquinoline have been synthesized through the reaction of the key intermediate thiosemicarbazide derivatives with different reagents. N?-Arylidene-4-oxo- 1,4-dihydroquinoline-3-carbohydrazides were also synthesized through the condensation reaction of the corresponding hydrazides with the appropriate aldehydes. Antimicrobial activity of some of the synthesized compounds was evaluated.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3522O – PubChem