Day: November 10, 2022

Velasco-Negueruela, A. published the artcileAnalysis by gas chromatography-mass spectrometry of the essential oil from the aerial parts of Pimpinella junoniae Ceb. & Ort., gathered in La Gomera, Canary Islands, Spain, Quality Control of 13391-27-0, the main research area is terpene arylpropanoid gas chromatog oil Pimpinella.

The essential oil from the aerial parts of Pimpinella junoniae Ceb.& Ort., growing in La Gomera, Canary Islands, Spain, was studied by gas chromatog. and gas chromatog.-mass spectrometry, and 43 constituents were identified. The major components were found to be α-zingiberene (20.6%), α-pinene (17.9%), (E)-β-farnesene (9.3%), ar-curcumene (7.4%), β-phellandrene (7.0%), β-bisabolene (6.1%) and epoxypseudoisoeugenyl 2-methylbutyrate (6.0%). The decomposition product of epoxypseudoisoeugenol derivatives, 5-methoxy-2-methylbenzofuran (5.7%), moderate amounts of other arylpropanoids with the pseudoisoeugenol skeleton (total percentage, 5.2%) and other compounds such as β-sesquiphellandrene (3.0%), cis-β-guaiene (1.5%), α-phellandrene (1.5%) and α-bisabolol (1.3%), were also found.

Journal of Chromatography A published new progress about Gas chromatography-mass spectrometry. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Quality Control of 13391-27-0.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Velasco-Negueruela, A. published the artcileAnalysis by gas chromatography-mass spectrometry of the essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species to the Canary Islands, Spain, Application of 5-Methoxy-2-methylbenzofuran, the main research area is terpene arylpropanoid essential oil Pimpinella GC MS.

The essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species growing in Tenerife, Canary Islands, Spain, were studied by gas chromatog. and gas chromatog.-mass spectrometry. The major components of the flowering tops (flowers + unripe fruits) of P. rupicola (PRFT) were found to be β-bisabolene (34.8%), limonene (10.9%) and α-zingiberene (10.5%), whereas in the flowering tops of P. anagodendron (PAFT), the main constituents were α-zingiberene (32.9%), β-bisabolene (17.9%), β-pinene (15.8%) and ar-curcumene (11.5%). The major compounds found in the stems + leaves of P. rupicola (PRSL) were β-bisabolene (31.6%), α-zingiberene (11.4%) and limonene (10.8%), whereas those of P. anagodendron (PASL) were α-zingiberene (32.3%), β-bisabolene (14.0%) and ar-curcumene (12.6%). In all the oils were found the characteristic constituents of genus Pimpinella, the pseudoisoeugenol esters. In accordance with the morphol., chorol. and chem. differences between both species, we suggest that P. rupicola Svent. is a good taxon and not a synonym of P. anagodendron.

Journal of Chromatography A published new progress about Gas chromatography-mass spectrometry. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Application of 5-Methoxy-2-methylbenzofuran.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Yamaguchi, Yuki published the artcileSynthetic Models Related to Methoxalen and Menthofuran-Cytochrome P450 (CYP) 2A6 Interactions. Benzofuran and Coumarin Derivatives as Potent and Selective Inhibitors of CYP2A6, HPLC of Formula: 50551-63-8, the main research area is benzofuran derivative preparation human microsomal cytochrome inhibitor; coumarin derivative preparation human microsomal cytochrome inhibitor; human microsomal cytochrome inhibitor reduce smoking tobacco cancer.

Human microsomal cytochrome P 450 (CYP) 2A6 contributes extensively to nicotine detoxication but also activates tobacco-specific procarcinogens to mutagenic products. A series of benzofuran and coumarin derivatives having inhibitory effects on the activity of human CYP2A6 have been described. Synthesized benzofuran I [IC50 = 2.20 μM] and coumarin II [R= 5-methoxy: IC50 = 0.13μM , R=6-methoxy: IC50 = 0.64 μM] derivatives were found to be more selective than methoxalen and menthofuran. These compounds can be used as a lead compounds in the design of CYP2A6 inhibitor drugs to reduce smoking and tobacco-related cancers.

Chemical & Pharmaceutical Bulletin published new progress about Coumarins Role: BSU (Biological Study, Unclassified), PAC (Pharmacological Activity), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), PREP (Preparation), USES (Uses). 50551-63-8 belongs to class benzofurans, name is 6-Methoxybenzofuran, and the molecular formula is C9H8O2, HPLC of Formula: 50551-63-8.

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem