Zhao, Liang et al. published their research in Sensors and Actuators, B: Chemical in 2020 | CAS: 76-54-0

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.SDS of cas: 76-54-0

A fluorescence turn-on assay for simple and sensitive determination of hemin and blood stains was written by Zhao, Liang;Chen, Fuqian;Huang, Wenyi;Bao, Huayu;Hu, Yingjie;Huang, Xin-an;Deng, Tao;Liu, Fang. And the article was included in Sensors and Actuators, B: Chemical in 2020.SDS of cas: 76-54-0 This article mentions the following:

Hemin, a sort of important Fe(III)-coordinated protoporphyrin IX complexes, plays critical roles in many biol. processes. Besides, hemin and its derivatives have been considered as biochem. markers to distinguish blood against other colored samples. The development of simple and sensitive methods for hemin determination is thus becoming important. In this research, a novel dihydrofluorescein derivative has been synthesized and applied as the fluorescence reporter. Inorganic H2O2 and organic tert-Bu hydroperoxide (TBHP), artemisinin (ART) have been used as peroxide sources to generate reactive radical species under hemin catalysis, which subsequently oxidize non fluorescent dihydrofluorescein to its fluorescent form. The limit of detection (LOD) was found down to picomolar levels (64 pM, 350 pM, 420 pM for H2O2, TBHP, ART systems resp.). Moreover, a simple detection strip has been prepared by incorporating both ART and fluorescence reporter into the filter papers, which offers a simple strategy to conveniently distinguish blood stains against other colored stains. In the experiment, the researchers used many compounds, for example, 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0SDS of cas: 76-54-0).

2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.SDS of cas: 76-54-0

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem